{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T13:15:35Z","timestamp":1777727735732,"version":"3.51.4"},"reference-count":21,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2019,10,8]],"date-time":"2019-10-08T00:00:00Z","timestamp":1570492800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Provincial Health and Family Planning Commission of Fujian Province","award":["2014-1-7"],"award-info":[{"award-number":["2014-1-7"]}]},{"name":"Fujian Major Program of Basic Science Project Foundation","award":["2014Y0006 and 2016J01496"],"award-info":[{"award-number":["2014Y0006 and 2016J01496"]}]},{"name":"Fujian Provincial Training project of Young Talents in Health System","award":["2013-ZQN-ZD-4"],"award-info":[{"award-number":["2013-ZQN-ZD-4"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2020,2]]},"abstract":"<jats:p>\n                    Protein-losing gastroenteropathy (PLGE) is a rare manifestation of primary Sj\u00f6gren\u2019s syndrome that is most commonly reported in Japan. Herein, the case of a 71-year-old Chinese male patient, diagnosed with PLGE and Sj\u00f6gren\u2019s syndrome, is reported. The patient presented with peripheral oedema, and PLGE was diagnosed based on the result of technetium-99m (\n                    <jats:sup>99m<\/jats:sup>\n                    Tc)-labelled albumin scintigraphy. In addition to a positive Schirmer\u2019s test, the patient had atrophy of the salivary gland with lymphocyte infiltration, impaired parotid-gland secretory and excretory function, and an increased level of anti-SSA antibodies, fulfilling the criteria for Sj\u00f6gren\u2019s syndrome. He was successfully treated with methylprednisolone. Follow-up\n                    <jats:sup>99m<\/jats:sup>\n                    Tc-labelled albumin scintigraphy results correlated well with clinical improvement and increased serum albumin levels. The present case study highlights the necessity of considering a diagnosis of protein loss enteropathy associated with primary Sj\u00f6gren\u2019s syndrome when patients have unexplained hypoproteinaemia.\n                  <\/jats:p>","DOI":"10.1177\/0300060519874543","type":"journal-article","created":{"date-parts":[[2019,10,9]],"date-time":"2019-10-09T01:51:56Z","timestamp":1570585916000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["A case report of Sj\u00f6gren\u2019s syndrome associated with protein-losing gastroenteropathy successfully treated with methylprednisolone"],"prefix":"10.1177","volume":"48","author":[{"given":"Xiaoming","family":"Li","sequence":"first","affiliation":[{"name":"Department of Geriatric Medicine, Fujian Provincial Hospital, Fujian Provincial Institute of Clinical Geriatrics, Fujian Provincial Key Laboratory of Geriatric Diseases, Fujian Medical University, Fuzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fan","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Geriatric Medicine, Fujian Provincial Hospital, Fujian Provincial Institute of Clinical Geriatrics, Fujian Provincial Key Laboratory of Geriatric Diseases, Fujian Medical University, Fuzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ziyu","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Geriatric Medicine, Fujian Provincial Hospital, Fujian Provincial Institute of Clinical Geriatrics, Fujian Provincial Key Laboratory of Geriatric Diseases, Fujian Medical University, Fuzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Geriatric Medicine, Fujian Provincial Hospital, Fujian Provincial Institute of Clinical Geriatrics, Fujian Provincial Key Laboratory of Geriatric Diseases, Fujian Medical University, Fuzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9922-5717","authenticated-orcid":false,"given":"Pengli","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Geriatric Medicine, Fujian Provincial Hospital, Fujian Provincial Institute of Clinical Geriatrics, Fujian Provincial Key Laboratory of Geriatric Diseases, Fujian Medical University, Fuzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,10,8]]},"reference":[{"key":"bibr1-0300060519874543","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(66)80081-1"},{"key":"bibr2-0300060519874543","first-page":"464","volume-title":"(eds) Sleisenger and Fordtran\u2019s Gastrointestinal and Liver Disease","author":"Greenwald DA.","year":"2016","edition":"1"},{"key":"bibr3-0300060519874543","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2018.01.009"},{"key":"bibr4-0300060519874543","doi-asserted-by":"publisher","DOI":"10.3390\/nu10081016"},{"key":"bibr5-0300060519874543","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2018.00432"},{"key":"bibr6-0300060519874543","doi-asserted-by":"publisher","DOI":"10.3109\/14397595.2016.1145570"},{"key":"bibr7-0300060519874543","doi-asserted-by":"publisher","DOI":"10.3109\/14397595.2013.844401"},{"key":"bibr8-0300060519874543","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2012.92"},{"key":"bibr9-0300060519874543","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-008-0794-2"},{"key":"bibr10-0300060519874543","doi-asserted-by":"publisher","DOI":"10.1080\/14397595.2018.1452335"},{"key":"bibr11-0300060519874543","doi-asserted-by":"publisher","DOI":"10.1177\/0961203315596078"},{"key":"bibr12-0300060519874543","first-page":"519","volume":"101","author":"Hsieh TY","year":"2002","journal-title":"J Formos Med Assoc"},{"key":"bibr13-0300060519874543","first-page":"1710","volume":"27","author":"Divgi CR","year":"1986","journal-title":"J Nucl Med"},{"key":"bibr14-0300060519874543","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2016-210571"},{"key":"bibr15-0300060519874543","doi-asserted-by":"publisher","DOI":"10.14309\/crj.2015.49"},{"key":"bibr16-0300060519874543","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(81)90506-0"},{"key":"bibr17-0300060519874543","doi-asserted-by":"publisher","DOI":"10.1007\/BF00253799"},{"key":"bibr18-0300060519874543","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2005.06.026"},{"key":"bibr19-0300060519874543","doi-asserted-by":"publisher","DOI":"10.2147\/CEG.S136803"},{"key":"bibr20-0300060519874543","doi-asserted-by":"publisher","DOI":"10.1007\/s005350070063"},{"key":"bibr21-0300060519874543","doi-asserted-by":"publisher","DOI":"10.1186\/1741-7015-11-95"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300060519874543","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0300060519874543","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300060519874543","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:50:14Z","timestamp":1777459814000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0300060519874543"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10,8]]},"references-count":21,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,2]]}},"alternative-id":["10.1177\/0300060519874543"],"URL":"https:\/\/doi.org\/10.1177\/0300060519874543","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,10,8]]},"article-number":"0300060519874543"}}