{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T12:51:35Z","timestamp":1777726295697,"version":"3.51.4"},"reference-count":13,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:p>Malignant peripheral nerve sheath tumor (MPNST) in the nasopharynx and oropharynx has not been reported. A 3-year-old boy was referred to hospital after experiencing intermittent inspiratory dyspnea for 3 years. Preoperative imaging showed that the lymph nodes were clear. Therefore, neck lymph node dissection was not performed during the operation. This could have reduced the collateral damage. Complete excision and radiotherapy were performed because of the pathological diagnosis of MPNST. Because of the high location of the tumor, we chose the transoral approach instead of the cervical approach, avoiding tracheotomy, and we effectively improved the quality of life of the child. A mass in the nasopharynx and oropharynx was diagnosed pathologically as an MPNST after surgery. The patient\u2019s inspiratory dyspnea was resolved. No recurrence was observed during a 3-year follow-up. After review of our case, we found that postoperative recovery in our patient was closely related to accurate preoperative imaging assessment, the choice of operation methods, thorough resection, and postoperative neoadjuvant radiotherapy. Prevertebral fascia acted as a barrier to surround the mass and prevented it from growing further toward the vertebral body, which was important for a good prognosis. Children undergoing tracheotomy often have long tube management and difficult extubation.<\/jats:p>","DOI":"10.1177\/0300060519897184","type":"journal-article","created":{"date-parts":[[2020,1,15]],"date-time":"2020-01-15T03:35:04Z","timestamp":1579059304000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Malignant peripheral nerve sheath tumor in the nasopharynx and oropharynx: a case report"],"prefix":"10.1177","volume":"48","author":[{"given":"Wen-Jing","family":"Gu","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology Head and Neck Surgery, the First Hospital of Jilin University, Changchun, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peng-yu","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, the First Hospital of Jilin University, Changchun, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ling-Jing","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Radiology, the Third People\u2019s Hospital of Shenzhen, Shenzhen, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Head and Neck Surgery, the First Hospital of Jilin University, Changchun, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1831-2195","authenticated-orcid":false,"given":"Hong-Wei","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Radiology, the Third People\u2019s Hospital of Shenzhen, Shenzhen, China"},{"name":"Department of Radiology, the first hospital of Jilin University, Changchun, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,1,15]]},"reference":[{"key":"bibr1-0300060519897184","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.22098"},{"key":"bibr2-0300060519897184","unstructured":"Weiss SGJ.\n                      Enzinger and Weiss's Soft Tissue Tumors\n                      . 4th ed. 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The WHO classification of tumors the nervous system.\n                      J Neuropathol Exp Neurol\n                      2000; 61: 215\u2013225.","DOI":"10.1093\/jnen\/61.3.215"},{"key":"bibr4-0300060519897184","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2010.02.009"},{"key":"bibr5-0300060519897184","doi-asserted-by":"publisher","DOI":"10.1159\/000241687"},{"key":"bibr6-0300060519897184","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.2008.01151.x"},{"key":"bibr7-0300060519897184","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-10-2799"},{"key":"bibr8-0300060519897184","doi-asserted-by":"publisher","DOI":"10.1097\/MPH.0b013e31822d4cef"},{"key":"bibr9-0300060519897184","first-page":"267","volume":"8","author":"Tosun HB","year":"2015","journal-title":"Int Med Case Rep J"},{"key":"bibr10-0300060519897184","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2009.06.063"},{"key":"bibr11-0300060519897184","doi-asserted-by":"crossref","unstructured":"Miller SJ, Rangwala F, Williams J, et al. Large-scale molecular comparison of human schwann cells to malignant peripheral nerve sheath tumor cell lines and tissues.\n                      Cancer Res\n                      2006; 66: 2584\u20132591.","DOI":"10.1158\/0008-5472.CAN-05-3330"},{"key":"bibr12-0300060519897184","doi-asserted-by":"publisher","DOI":"10.1002\/hed.20537"},{"key":"bibr13-0300060519897184","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2015.134"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300060519897184","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0300060519897184","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300060519897184","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:45:59Z","timestamp":1777459559000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0300060519897184"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,1]]}},"alternative-id":["10.1177\/0300060519897184"],"URL":"https:\/\/doi.org\/10.1177\/0300060519897184","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1]]},"article-number":"0300060519897184"}}