{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T14:27:00Z","timestamp":1779114420651,"version":"3.51.4"},"reference-count":27,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T00:00:00Z","timestamp":1590969600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Guide Funding from Renmin Hospital of Wuhan University","award":["RMYD2018M42"],"award-info":[{"award-number":["RMYD2018M42"]}]},{"name":"Guide Funding from Renmin Hospital of Wuhan University","award":["RMYD2018Z13"],"award-info":[{"award-number":["RMYD2018Z13"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2020,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aimed to compare the pregnancy outcomes between women receiving frozen embryo transfer (FET) with hormone replacement treatment (HRT) with and without gonadotropin-releasing hormone agonist (GnRHa) pretreatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>All consecutive women undergoing HRT cycles (2936 cycles) or HRT with GnRHa pretreatment (HRT\u2009+\u2009GnRHa, 303 cycles) at our reproductive center between January 2015 and December 2017 were analyzed retrospectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The average age was higher in the HRT\u2009+\u2009GnRHa compared with the HRT group (34.0\u2009\u00b1\u20094.8 vs. 31.3\u2009\u00b1\u20094.4). However, the pregnancy outcomes were comparable between the two groups. The clinical pregnancy rate was significantly increased in younger women (\u226435 years) in the HRT\u2009+\u2009GnRHa group compared with the HRT group (56.8% vs. 48.7%), but the live birth rates were similar in the two groups (44.2% vs. 38.4%). The HRT\u2009+\u2009GnRHa protocol significantly increased the clinical pregnancy rate (55.6% vs. 43.2%) and live birth rate (43.5% vs. 33.5%) compared with the HRT group among women with endometriosis, and significantly decreased the abortion rate in women with polycystic ovarian syndrome (3.1% vs. 16.4%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>GnRHa pretreatment may improve pregnancy outcomes in women with endometriosis and polycystic ovarian syndrome.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0300060520918474","type":"journal-article","created":{"date-parts":[[2020,6,26]],"date-time":"2020-06-26T04:41:41Z","timestamp":1593146501000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":18,"title":["Effects of artificial cycles with and without gonadotropin-releasing hormone agonist pretreatment on frozen embryo transfer outcomes"],"prefix":"10.1177","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0276-7187","authenticated-orcid":false,"given":"Qianrong","family":"Qi","sequence":"first","affiliation":[{"name":"Center for Reproductive Medicine, Renmin Hospital of Wuhan University, Wuhan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin","family":"Luo","sequence":"additional","affiliation":[{"name":"Center for Reproductive Medicine, Renmin Hospital of Wuhan University, Wuhan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yaqin","family":"Wang","sequence":"additional","affiliation":[{"name":"Center for Reproductive Medicine, Renmin Hospital of Wuhan University, Wuhan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingzhen","family":"Xie","sequence":"additional","affiliation":[{"name":"Center for Reproductive Medicine, Renmin Hospital of Wuhan University, Wuhan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,6,26]]},"reference":[{"key":"bibr1-0300060520918474","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1705334"},{"key":"bibr2-0300060520918474","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1513873"},{"key":"bibr3-0300060520918474","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dev339"},{"key":"bibr4-0300060520918474","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2016.01.006"},{"key":"bibr5-0300060520918474","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dex285"},{"key":"bibr6-0300060520918474","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-016-0736-y"},{"key":"bibr7-0300060520918474","first-page":"1","volume":"9","author":"Azimi Nekoo E","year":"2015","journal-title":"J Family Reprod 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