{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T20:35:13Z","timestamp":1792787713176,"version":"4.5.0"},"reference-count":21,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"CAMS Innovation Fund for Medical Sciences","award":["No. 2018-I2M-1-004"],"award-info":[{"award-number":["No. 2018-I2M-1-004"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["No. 81671448 and No. 81871152"],"award-info":[{"award-number":["No. 81671448 and No. 81871152"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate the effect of early-life unilateral testicular torsion on adult male fertility.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Clinical information was collected for 122 patients who had experienced unilateral testicular torsion at a median age of 15.5 years. The recent pregnancy rate and time to pregnancy experienced by the patients\u2019 female partners were assessed by structured interviews. Data were analyzed by the chi-squared test and Student\u2019s t-test.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Seventy-two patients with testicular torsion met the criteria for inclusion in our analyses; 49 had undergone orchiectomy, while 23 had undergone surgical repositioning\/orchiopexy. The pregnancy rate and median time to pregnancy were 83.67% (41\/49) and 1.6 years, respectively, in the orchiectomy group, whereas they were 91.30% (21\/23) and 0.75 years, respectively, in the repositioning\/orchiopexy group. The recent pregnancy rate was higher in patients with torsion in childhood than in patients with torsion in adolescence; it was lowest in patients with torsion in adulthood. Surgical repositioning\/orchiopexy yielded a significantly better recent pregnancy rate among the three groups, based on age at the time of torsion, and a shorter time to pregnancy than orchiectomy in patients with torsion in adolescence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Onset of unilateral testicular torsion early in life has a negligible effect on adult male fertility.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0300060520918792","type":"journal-article","created":{"date-parts":[[2020,4,21]],"date-time":"2020-04-21T07:03:26Z","timestamp":1587452606000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":26,"title":["Effect of unilateral testicular torsion at different ages on male fertility"],"prefix":"10.1177","volume":"48","author":[{"given":"Xinyu","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Urology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China"},{"name":"Department of Urology, The Sixth Medical Centre, Chinese PLA General Hospital, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianzhong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Urology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8098-8922","authenticated-orcid":false,"given":"Zhonglin","family":"Cai","sequence":"additional","affiliation":[{"name":"Department of Urology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiyou","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Urology, The Sixth Medical Centre, Chinese PLA General Hospital, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenhong","family":"Lu","sequence":"additional","affiliation":[{"name":"NHC Key Laboratory of Male Reproductive Health, National Research Institute for Family Planning & WHO Collaborating Center for Research in Human Reproduction, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6040-5251","authenticated-orcid":false,"given":"Hongjun","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Urology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,4,21]]},"reference":[{"key":"bibr1-0300060520918792","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.h1563"},{"key":"bibr2-0300060520918792","first-page":"18","volume":"32","author":"Pubab M","year":"2017","journal-title":"Hum 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