{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T12:57:28Z","timestamp":1787317048802,"version":"build-2736575974"},"reference-count":23,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Important Weak Subject Construction Project of Pudong Health and Fanily Planning Commission of Shanghai","award":["PWZbr2017-25"],"award-info":[{"award-number":["PWZbr2017-25"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate the clinical manifestations of infectious mononucleosis in children of different ages.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Clinical data from pediatric patients with infectious mononucleosis admitted from May 2015 to April 2019 were retrospectively analyzed. Patients were stratified into three groups (age 1\u20133 years, 4\u20136 years, and 7\u201314 years) for analysis of clinical and laboratory results.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Data from 61 patients (male:female ratio 1.18:1) aged 5.15\u2009\u00b1\u20092.93 years (mean\u2009\u00b1\u2009standard deviation; range: 1\u201314 years) were analyzed. Infectious mononucleosis occurred throughout the year and the main clinical manifestations were fever (98.3%), tonsillitis (100%), tonsillar white exudate (83.6%), cervical lymphadenopathy (98.3%), hepatomegaly (37.7%), splenomegaly (42.6%), eyelid edema (41.0%), and nasal obstruction (49.2%). Disease onset was most common during early childhood (37.7%) and at preschool age (37.7%). Younger children had more obvious symptoms of nasal obstruction and older children had more significant elevations of alanine aminotransferase and higher percentages of atypical lymphocytes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The clinical manifestations of infectious mononucleosis in children differed by age. These associations required attention for clinical decision making.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0300060520924550","type":"journal-article","created":{"date-parts":[[2020,10,13]],"date-time":"2020-10-13T00:35:45Z","timestamp":1602549345000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":38,"title":["Clinical manifestations and laboratory results of 61 children with infectious mononucleosis"],"prefix":"10.1177","volume":"48","author":[{"given":"Yanming","family":"Wu","sequence":"first","affiliation":[{"name":"Department of Pediatrics, People\u2019s Hospital of Shanghai Pudong New District, Shanghai University of Medicine and Health Sciences, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suli","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, People\u2019s Hospital of Shanghai Pudong New District, Shanghai University of Medicine and Health Sciences, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingjun","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, People\u2019s Hospital of Shanghai Pudong New District, Shanghai University of Medicine and Health Sciences, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daoming","family":"Zu","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, People\u2019s Hospital of Shanghai Pudong New District, Shanghai University of Medicine and Health Sciences, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fangjin","family":"Gu","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, People\u2019s Hospital of Shanghai Pudong New District, Shanghai University of Medicine and Health Sciences, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyuan","family":"Ding","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, People\u2019s Hospital of Shanghai Pudong New District, Shanghai University of Medicine and Health Sciences, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3564-495X","authenticated-orcid":false,"given":"Lei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, People\u2019s Hospital of Shanghai Pudong New District, Shanghai University of Medicine and Health Sciences, Shanghai, 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