{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T12:20:40Z","timestamp":1778588440378,"version":"3.51.4"},"reference-count":16,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:p>Branchial cleft abnormality is a common congenital neck malformation in children, which is caused by the abnormal development of the gill sac or gill groove. It is mainly manifested as a cyst in the sinus tract and fistula in the neck, as well as branchio-oto-renal syndrome (BORS). As a rare autosomal dominant genetic disease, the typical manifestations of BORS are hearing loss, abnormal branchial cleft development and renal dysplasia. In this paper, a patient was admitted to the hospital for bilateral branchial cleft fistulas combined with bilateral anterior auricular fistulas, auricular appendix, auricle dysplasia, external auditory canal stenosis, and hearing loss. The patient was diagnosed with BORS, and underwent fistulectomy of the neck and anterior ear, external auditory canal formation, and tympanoplasty. The aim of this report is to strengthen clinicians\u2019 understanding of BORS and reduce the rate of clinical missed diagnosis through our case report and literature review.<\/jats:p>","DOI":"10.1177\/0300060520926363","type":"journal-article","created":{"date-parts":[[2020,7,21]],"date-time":"2020-07-21T03:31:57Z","timestamp":1595302317000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":10,"title":["Branchial cleft fistula to branchio-oto-renal syndrome: A case report and literature review"],"prefix":"10.1177","volume":"48","author":[{"given":"Hong-Xia","family":"Li","sequence":"first","affiliation":[{"name":"Otorhinolaryngology Head and Neck Surgery, West China-Guang\u2019an Hospital, Sichuan University, Guang\u2019an, Sichuan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peng","family":"Zhou","sequence":"additional","affiliation":[{"name":"Otorhinolaryngology Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min","family":"Tong","sequence":"additional","affiliation":[{"name":"Otorhinolaryngology Head and Neck Surgery, Leshan People\u2019s Hospital, Leshan, Sichuan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5515-3667","authenticated-orcid":false,"given":"Yan","family":"Zheng","sequence":"additional","affiliation":[{"name":"Otorhinolaryngology Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,7,21]]},"reference":[{"key":"bibr1-0300060520926363","doi-asserted-by":"publisher","DOI":"10.1111\/ped.12357"},{"key":"bibr2-0300060520926363","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320070316"},{"key":"bibr3-0300060520926363","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-0709(79)80003-4"},{"key":"bibr4-0300060520926363","doi-asserted-by":"publisher","DOI":"10.11622\/smedj.2015060"},{"key":"bibr5-0300060520926363","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-012-2287-x"},{"key":"bibr6-0300060520926363","first-page":"121","volume":"11","author":"Melnick M","year":"1975","journal-title":"Birth Defects Orig Artic Ser"},{"key":"bibr7-0300060520926363","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320020305"},{"key":"bibr8-0300060520926363","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/6.13.2247"},{"key":"bibr9-0300060520926363","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-5876(01)00473-6"},{"key":"bibr10-0300060520926363","doi-asserted-by":"publisher","DOI":"10.1177\/0145561318824227"},{"key":"bibr11-0300060520926363","doi-asserted-by":"publisher","DOI":"10.1177\/2058460119861606"},{"key":"bibr12-0300060520926363","doi-asserted-by":"publisher","DOI":"10.1080\/14992020400050067"},{"key":"bibr13-0300060520926363","first-page":"1226","volume":"32","author":"Wen YY","year":"2018","journal-title":"Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi"},{"key":"bibr14-0300060520926363","doi-asserted-by":"publisher","DOI":"10.1007\/s00439-013-1338-8"},{"key":"bibr15-0300060520926363","volume-title":"GeneReviews(\u00ae)","author":"Smith RJH.","year":"1993"},{"key":"bibr16-0300060520926363","doi-asserted-by":"publisher","DOI":"10.1038\/s10038-018-0429-8"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300060520926363","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0300060520926363","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300060520926363","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:47:09Z","timestamp":1777459629000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0300060520926363"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7]]},"references-count":16,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2020,7]]}},"alternative-id":["10.1177\/0300060520926363"],"URL":"https:\/\/doi.org\/10.1177\/0300060520926363","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7]]},"article-number":"0300060520926363"}}