{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T12:54:41Z","timestamp":1777726481556,"version":"3.51.4"},"reference-count":19,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T00:00:00Z","timestamp":1590969600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T00:00:00Z","timestamp":1590969600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Youth program of Shanghai Municipal Health Bureau","award":["20144Y0260"],"award-info":[{"award-number":["20144Y0260"]}]},{"name":"Shanghai Science and Technology Commission Western Medicine Guidance Project","award":["16411960500"],"award-info":[{"award-number":["16411960500"]}]},{"name":"National Natural Science Foundation of China for Youth Program","award":["81500779"],"award-info":[{"award-number":["81500779"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2020,6]]},"abstract":"<jats:p>This study was performed to investigate the feasibility of using a three-dimensional (3D) finite element model for laryngomalacia severity assessment. We analyzed laryngeal computed tomography images of seven children with laryngomalacia using Mimics software. The gray threshold of different tissues was distinguishable, and a 3D visualization model and finite element model were constructed. The laryngeal structure parameters were defined. The peak von Mises stress (PVMS) value was obtained through laryngeal mechanical analysis. The PVMS values of the laryngeal soft tissue and cartilage scaffolds were independently correlated with disease severity. After stress loading the model, the relationship between laryngomalacia severity and the PVMS value was apparent. However, the PVMS value of laryngeal soft tissue was not correlated with laryngomalacia severity. This study established the efficacy of a finite element model to illustrate the morphological features of the laryngeal cavity in infants with laryngomalacia. However, further study is required before widespread application of 3D finite element modeling of laryngomalacia. PVMS values of the laryngeal cartilage scaffold might be useful for assessment of laryngomalacia severity. These findings support the notion that structural abnormalities of the laryngeal cartilage may manifest as quantifiable changes in stress variants of the supraglottic larynx.<\/jats:p>","DOI":"10.1177\/0300060520926407","type":"journal-article","created":{"date-parts":[[2020,6,4]],"date-time":"2020-06-04T02:27:47Z","timestamp":1591237667000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Three-dimensional finite element modeling for evaluation of laryngomalacia severity in infants and children"],"prefix":"10.1177","volume":"48","author":[{"given":"Hongming","family":"Xu","sequence":"first","affiliation":[{"name":"Department of Otolaryngology- Head and Neck Surgery, Children\u2019s Hospital of Shanghai, <!---->Shanghai Jiao Tong University<!---->, Shanghai, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiali","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology- Head and Neck Surgery, Children\u2019s Hospital of Shanghai, <!---->Shanghai Jiao Tong University<!---->, Shanghai, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shilei","family":"Pu","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology- Head and Neck Surgery, Children\u2019s Hospital of Shanghai, <!---->Shanghai Jiao Tong University<!---->, Shanghai, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3080-9321","authenticated-orcid":false,"given":"Xiaoyan","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology- Head and Neck Surgery, Children\u2019s Hospital of Shanghai, <!---->Shanghai Jiao Tong University<!---->, Shanghai, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,6,3]]},"reference":[{"key":"e_1_3_7_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.prrv.2006.04.227"},{"key":"e_1_3_7_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199911000-00009"},{"key":"e_1_3_7_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/MLG.0b013e31804a5750"},{"key":"e_1_3_7_5_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.131.4.340"},{"key":"e_1_3_7_6_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1984.00800340058017"},{"key":"e_1_3_7_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2014.04.015"},{"key":"e_1_3_7_8_2","doi-asserted-by":"publisher","DOI":"10.1177\/0003489415585869"},{"key":"e_1_3_7_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-016-3943-3"},{"key":"e_1_3_7_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.matdes.2018.04.065"},{"key":"e_1_3_7_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmbbm.2015.04.002"},{"key":"e_1_3_7_12_2","first-page":"891","article-title":"Establishment and preliminary application of a laryngomalacia larynx three-dimension model","volume":"32","author":"Xu HM","year":"2018","unstructured":"Xu HM, Pu SL, Jiang YG, et\u00a0al. 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