{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T23:31:46Z","timestamp":1792798306797,"version":"4.5.0"},"reference-count":30,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T00:00:00Z","timestamp":1590969600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Science and Technology Program of Guangzhou","award":["201707010451"],"award-info":[{"award-number":["201707010451"]}]},{"name":"Medical Science and Technology Research of Guangdong Province","award":["A2016056"],"award-info":[{"award-number":["A2016056"]}]},{"DOI":"10.13039\/501100015806","name":"The Project for Key Medicine Discipline Construction of Guangzhou Municipality","doi-asserted-by":"crossref","award":["2017-2019-07"],"award-info":[{"award-number":["2017-2019-07"]}],"id":[{"id":"10.13039\/501100015806","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Major projects of Guangzhou Municipal Health and Family Planning Commission","award":["2018A031002"],"award-info":[{"award-number":["2018A031002"]}]},{"name":"Medical Science Foundation of Guangdong","award":["B201849"],"award-info":[{"award-number":["B201849"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2020,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To explore associations between temperature, humidity and hand, foot and mouth disease (HFMD) incidence in Guangzhou, China from 2013 to 2017.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A distributed lag non-linear model was applied to estimate the effects of daily temperature and humidity on HFMD incidence after adjusting for long-term trends, seasonal trends, and day of the week.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In total, 353,431 confirmed HFMD cases were reported in Guangzhou over the study period. A bimodal seasonal pattern was observed. High temperatures had acute short-term effects on HFMD incidence that declined quickly over time. The effects of low humidity declined over lag periods, but increased when the humidity surpassed 60.5%. Temperature and humidity were both inversely associated with HFMD incidence during lag days 0 to 3 and with lag periods<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Temperature and humidity play important roles in HFMD incidence. These data are important for developing public health strategies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0300060520929895","type":"journal-article","created":{"date-parts":[[2020,6,12]],"date-time":"2020-06-12T04:36:12Z","timestamp":1591936572000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":16,"title":["Influence of temperature and humidity on hand, foot, and mouth disease in Guangzhou, 2013\u20132017"],"prefix":"10.1177","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8336-8844","authenticated-orcid":false,"given":"Chun","family":"Chen","sequence":"first","affiliation":[{"name":"Guangzhou Center for Disease Control and Prevention, Guangzhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qinqin","family":"Jiang","sequence":"additional","affiliation":[{"name":"Guangzhou Center for Disease Control and Prevention, Guangzhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhuangzhi","family":"Song","sequence":"additional","affiliation":[{"name":"Center for Disease Control and Prevention of Inner Mongolia Autonomous Region, Hohhot, Inner Mongolia Autonomous Region, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yilan","family":"Li","sequence":"additional","affiliation":[{"name":"Guangzhou Center for Disease Control and Prevention, Guangzhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Wang","sequence":"additional","affiliation":[{"name":"Guangzhou Center for Disease Control and Prevention, Guangzhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Lu","sequence":"additional","affiliation":[{"name":"Guangzhou Center for Disease Control and Prevention, Guangzhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dahu","family":"Wang","sequence":"additional","affiliation":[{"name":"Guangzhou Center for Disease Control and Prevention, Guangzhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meixia","family":"Li","sequence":"additional","affiliation":[{"name":"Guangzhou Center for Disease Control and Prevention, Guangzhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiegang","family":"Li","sequence":"additional","affiliation":[{"name":"Guangzhou Chest Hospital, Guangzhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,6,12]]},"reference":[{"key":"bibr1-0300060520929895","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199909233411301"},{"key":"bibr2-0300060520929895","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6976.2002.tb00601.x"},{"key":"bibr3-0300060520929895","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa065954"},{"key":"bibr4-0300060520929895","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000001242"},{"key":"bibr5-0300060520929895","unstructured":"National Health and Family Planning Commission. 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