{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T16:04:31Z","timestamp":1790352271818,"version":"4.1.0"},"reference-count":27,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T00:00:00Z","timestamp":1590969600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"The Natural Science Foundation project of Zhejiang province, China","award":["No. LQ15H030001"],"award-info":[{"award-number":["No. LQ15H030001"]}]},{"name":"Medical and Health Science Project of Zhejiang Province, People\u2019s Republic of China","award":["(No.2017192063)"],"award-info":[{"award-number":["(No.2017192063)"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2020,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The purpose of this study was to compare the pregnancy outcomes among young patients with occult premature ovarian insufficiency (OPOI), advanced-age patients with diminished ovarian reserve (DOR), and advanced-age patients with normal ovarian reserve.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively reviewed 324 women who underwent their first cycles of in vitro fertilization\/intracytoplasmic sperm injection. The women were divided into the following groups: young women with OPOI, advanced-age women with DOR, and advanced-age women with normal ovarian reserve. The outcomes were compared among the different groups:<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The rates of live birth and embryo implantation in the young OPOI group were significantly higher than in the advanced-age DOR group, but comparable to those in the advanced-age normal ovarian reserve group. Moreover, the abortion rate was significantly lower in young OPOI patients compared with advanced-age patients with or without DOR.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Higher embryo implantation and live birth rates and a lower abortion rate can be achieved in young patients with OPOI compared with older patients. The better outcomes in advanced-age patients with normal ovarian reserve compared with DOR may be related to egg quantity rather than quality.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0300060520934656","type":"journal-article","created":{"date-parts":[[2020,6,26]],"date-time":"2020-06-26T03:46:40Z","timestamp":1593143200000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Comparative study of assisted reproductive outcomes between young patients with occult premature ovarian insufficiency and advanced-age patients"],"prefix":"10.1177","volume":"48","author":[{"given":"Ling-nv","family":"Yao","sequence":"first","affiliation":[{"name":"Reproductive Medical Center, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-qin","family":"Lin","sequence":"additional","affiliation":[{"name":"Reproductive Medical Center, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nan","family":"Jiang","sequence":"additional","affiliation":[{"name":"Reproductive Medical Center, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuyan","family":"Li","sequence":"additional","affiliation":[{"name":"Reproductive Medical Center, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hai-feng","family":"Cao","sequence":"additional","affiliation":[{"name":"Reproductive Medical Center, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, 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