{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,14]],"date-time":"2026-11-14T08:04:08Z","timestamp":1794643448172,"version":"4.9.1"},"reference-count":15,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T00:00:00Z","timestamp":1590969600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2020,6]]},"abstract":"<jats:p>Sarcomatoid carcinoma is a rare type of gallbladder cancer with no specific clinical manifestation. The final diagnosis depends on pathological and immunohistochemical examination. Sarcomatoid carcinoma is characterized by early lymphatic metastasis, rapid progression, a high short-term recurrence rate, and a worse prognosis than adenocarcinoma. This report describes a 60-year-old woman with poorly differentiated adenocarcinoma of the gallbladder. She underwent treatment with chemotherapy and surgery. Palliative surgery was performed for treatment of tumor recurrence in April 2018. Postoperative pathology showed infiltration of poorly differentiated carcinomas, most of which were sarcomatoid. After four cycles of chemotherapy, the disease continued to progress. Anlotinib tablets were given from August 2018 to November 2018 but were then stopped because of gastrointestinal bleeding. The patient died in April 2019. This paper reports the whole process of diagnosis and treatment in this case of gallbladder sarcomatoid carcinoma, thus providing a reference for treatment.<\/jats:p>","DOI":"10.1177\/0300060520935283","type":"journal-article","created":{"date-parts":[[2020,6,26]],"date-time":"2020-06-26T21:23:34Z","timestamp":1593206614000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["Sarcomatoid carcinoma of the gallbladder: a case report"],"prefix":"10.1177","volume":"48","author":[{"given":"Yunfu","family":"Shi","sequence":"first","affiliation":[{"name":"Department of Oncology, Tongde Hospital of Zhejiang Province, Hangzhou, China"},{"name":"The First School of Medicine, Zhejiang Chinese Medical University, Hangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiabin","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Oncology, Tongde Hospital of Zhejiang Province, Hangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Oncology, Tongde Hospital of Zhejiang Province, Hangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9789-982X","authenticated-orcid":false,"given":"Xiufang","family":"Hong","sequence":"additional","affiliation":[{"name":"Department of Geriatrics, Zhejiang Hospital, Hangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,6,26]]},"reference":[{"key":"bibr1-0300060520935283","doi-asserted-by":"publisher","DOI":"10.1093\/jscr\/2012.2.5"},{"key":"bibr2-0300060520935283","doi-asserted-by":"publisher","DOI":"10.1007\/s12029-014-9654-3"},{"key":"bibr3-0300060520935283","doi-asserted-by":"publisher","DOI":"10.3350\/kjhep.2010.16.1.89"},{"key":"bibr4-0300060520935283","doi-asserted-by":"publisher","DOI":"10.7314\/APJCP.2012.13.11.5613"},{"key":"bibr5-0300060520935283","first-page":"99","volume":"6","author":"Hundal R","year":"2014","journal-title":"Clin Epidemiol"},{"key":"bibr6-0300060520935283","first-page":"175","volume":"9","author":"Hu ZH","year":"2010","journal-title":"Hepatobiliary Pancreat Dis Int"},{"key":"bibr7-0300060520935283","first-page":"247","volume":"42","author":"Qin Y","year":"2015","journal-title":"Chin J Clin Oncol"},{"key":"bibr8-0300060520935283","first-page":"2063","volume":"24","author":"Chang X","year":"2016","journal-title":"Shijie Huaren Xiaohua Zazhi"},{"key":"bibr9-0300060520935283","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1827.2004.01771.x"},{"key":"bibr10-0300060520935283","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.15.1876"},{"key":"bibr11-0300060520935283","doi-asserted-by":"publisher","DOI":"10.1038\/srep30038"},{"key":"bibr12-0300060520935283","doi-asserted-by":"publisher","DOI":"10.1186\/s13045-016-0332-8"},{"key":"bibr13-0300060520935283","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2018.3039"},{"key":"bibr14-0300060520935283","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2018.0022"},{"key":"bibr15-0300060520935283","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-17-3766"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300060520935283","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0300060520935283","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300060520935283","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:47:03Z","timestamp":1777459623000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0300060520935283"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6]]},"references-count":15,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2020,6]]}},"alternative-id":["10.1177\/0300060520935283"],"URL":"https:\/\/doi.org\/10.1177\/0300060520935283","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,6]]},"article-number":"0300060520935283"}}