{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T12:53:07Z","timestamp":1777726387807,"version":"3.51.4"},"reference-count":26,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T00:00:00Z","timestamp":1596240000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"the youth Program of Changshu Health Bureau","award":["CSWSQ201401"],"award-info":[{"award-number":["CSWSQ201401"]}]},{"name":"Suzhou Health Human Resources Development Project","award":["GSWS2019037"],"award-info":[{"award-number":["GSWS2019037"]}]},{"name":"Science and Technology Plan of Changshu City Health Commission","award":["CSWS201906"],"award-info":[{"award-number":["CSWS201906"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study investigated whether the CYP11B2 -344T\/C polymorphism is correlated with transient ischemic attack (TIA) susceptibility.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We recruited 100 TIA patients and 100 control subjects and analyzed the CYP11B2 -344T\/C polymorphism using restriction fragment length polymorphism (PCR\u2013RFLP).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The frequency in TIA patients and controls was 42% compared with 48% for TT genotypes, 51% compared with 45% for TC genotypes, and 7% compared with 7% for CC genotype, respectively. Allele frequencies in TIA patients and controls were 67.5% compared with 70.5% for T-allele and 32.5% compared with 29.5% for C-allele, respectively. No association between the CYP11B2 -344T\/C polymorphism and TIA was observed in all comparisons.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our data suggest that there was no association between the CYP11B2 -344T\/C polymorphism and TIA in a Chinese population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0300060520947916","type":"journal-article","created":{"date-parts":[[2020,8,13]],"date-time":"2020-08-13T13:21:36Z","timestamp":1597324896000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Lack of association between CYP11B2 -344T\/C polymorphism and transient ischemic attack in a Chinese population"],"prefix":"10.1177","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2924-2156","authenticated-orcid":false,"given":"Jia","family":"Fan","sequence":"first","affiliation":[{"name":"Changshu First People\u2019s Hospital Affiliated to Soochow University, Changshu, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yaoliang","family":"Shen","sequence":"additional","affiliation":[{"name":"Changshu First People\u2019s Hospital Affiliated to Soochow University, Changshu, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo","family":"Chen","sequence":"additional","affiliation":[{"name":"Changshu First People\u2019s Hospital Affiliated to Soochow University, Changshu, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chunyang","family":"Xu","sequence":"additional","affiliation":[{"name":"Changshu First People\u2019s Hospital Affiliated to Soochow University, Changshu, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0374-5406","authenticated-orcid":false,"given":"Hongwei","family":"Ye","sequence":"additional","affiliation":[{"name":"Changshu First People\u2019s Hospital Affiliated to Soochow University, Changshu, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian","family":"Wang","sequence":"additional","affiliation":[{"name":"The Fifth People's Hospital of Changshu, Changshu, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3312-9321","authenticated-orcid":false,"given":"Wenjun","family":"Zhou","sequence":"additional","affiliation":[{"name":"The Fifth People's Hospital of Changshu, Changshu, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuefeng","family":"Sheng","sequence":"additional","affiliation":[{"name":"Changshu Medical Emergency Center, Changshu, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feng","family":"Xu","sequence":"additional","affiliation":[{"name":"Emergency Department, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2967-4108","authenticated-orcid":false,"given":"Peng","family":"Yang","sequence":"additional","affiliation":[{"name":"Emergency Department, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,8,13]]},"reference":[{"key":"bibr1-0300060520947916","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000152"},{"key":"bibr2-0300060520947916","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000152985.32732.EE"},{"key":"bibr3-0300060520947916","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.114.006768"},{"key":"bibr4-0300060520947916","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2015.05.016"},{"key":"bibr5-0300060520947916","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.109.575373"},{"key":"bibr6-0300060520947916","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2013-2805"},{"key":"bibr7-0300060520947916","first-page":"1","author":"Niu S","year":"2015","journal-title":"Clin Exp 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