{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T12:53:11Z","timestamp":1777726391600,"version":"3.51.4"},"reference-count":11,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:p>Perivascular epithelioid cell tumor (PEComa) is a rare mesenchymal tumor with unique histological and immunohistochemical characteristics. Malignant renal cell carcinoma is even rarer and its biological behavior is still not clear. We report here a case of malignant PEComa in a male patient. The first symptom of the patient was intermittent hematuria. Ultrasound and computed tomography scan showed a solid mass in the left kidney. Fibrosarcoma was initially diagnosed after radical resection of the tumor. Six years later, the patient had a tumor recurrence and underwent a second operation, through which the diagnosis of renal malignant PEComa was made. Since then, the patient received chemotherapy, a third operation, and interventional treatment because of recurrence and metastasis of the tumor, which prolonged the life of the patient for another 6 years. Malignant PEComa involving the kidney is very rare; it seems to develop slowly but will recur and metastasize. At present, surgical resection remains the best treatment.<\/jats:p>","DOI":"10.1177\/0300060520961223","type":"journal-article","created":{"date-parts":[[2020,10,19]],"date-time":"2020-10-19T21:35:08Z","timestamp":1603143308000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["Perivascular epithelioid cell tumor (PEComa) of the kidney: an overview of its management and outcomes"],"prefix":"10.1177","volume":"48","author":[{"given":"Yu","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Urology, the Fourth Medical Center of PLA General Hospital, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaohong","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Urology, the Linyi People\u2019s Hospital, Linyi, Shandong Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Surgery, the Maternal and Child Health Hospital of Pingyi County, Linyi, Shandong Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0959-3474","authenticated-orcid":false,"given":"Zhiqiang","family":"Shao","sequence":"additional","affiliation":[{"name":"Department of Urology, the Linyi People\u2019s Hospital, Linyi, Shandong Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,10,18]]},"reference":[{"key":"bibr1-0300060520961223","unstructured":"Fletcher CD, Unni KK, Mertens F.\n                      Pathology and genetics of tumours of soft tissue and bone\n                      . 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