{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T12:53:21Z","timestamp":1777726401886,"version":"3.51.4"},"reference-count":15,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Zhejiang medical science and technology projects","award":["2018KY056"],"award-info":[{"award-number":["2018KY056"]}]},{"DOI":"10.13039\/501100010248","name":"Public Welfare Technology Application Research Project of Zhejiang Province","doi-asserted-by":"crossref","award":["2016C37119"],"award-info":[{"award-number":["2016C37119"]}],"id":[{"id":"10.13039\/501100010248","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:p>Autoimmune polyglandular syndrome (APS) is a rare disease that is characterized by autoimmune reactions to multiple endocrine and non-endocrine organs, which can be divided into four main types. The principal manifestations of APS-3 are autoimmune thyroid disease and other autoimmune diseases, such as type 1 diabetes, atrophic gastritis, pernicious anemia, vitiligo, alopecia, and myasthenia gravis, but not Addison\u2019s disease or hypoparathyroidism. Here we report a case demonstrating the rare coexistence of growth hormone deficiency and hyperthyroidism with sexual dysgenesis, secondary amenorrhea, cardiomegaly, splenomegaly, hypoproteinemia, pleural effusion, seroperitoneum, pericardial effusion, anasarca, osteoporosis, vitamin D deficiency, iron-deficiency anemia, poor blood coagulation, leucocytopenia, peripheral neuropathy, hyperuricemia, ichthyosis, tinea cruris, and onychomycosis.<\/jats:p>","DOI":"10.1177\/0300060520961684","type":"journal-article","created":{"date-parts":[[2020,10,13]],"date-time":"2020-10-13T01:08:37Z","timestamp":1602551317000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["A rare case of coexistence of autoimmune polyglandular syndrome type 3 with growth hormone deficiency and hyperthyroidism in a patient with pseudo-Turner\u2019s syndrome"],"prefix":"10.1177","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9680-5441","authenticated-orcid":false,"given":"Weibin","family":"Zhou","sequence":"first","affiliation":[{"name":"Department of Endocrinology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haiyang","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, the Affiliated Wenling Hospital, Wenzhou Medical University; Wenling, Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianwen","family":"Ning","sequence":"additional","affiliation":[{"name":"Department of Emergency, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,10,12]]},"reference":[{"key":"bibr1-0300060520961684","doi-asserted-by":"publisher","DOI":"10.1016\/j.ando.2009.12.013"},{"key":"bibr2-0300060520961684","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1002\/ajh.25495","volume":"94","author":"Dispenzieri A.","year":"2019","journal-title":"Am J Hematol"},{"key":"bibr3-0300060520961684","doi-asserted-by":"publisher","DOI":"10.1007\/BF03346552"},{"key":"bibr4-0300060520961684","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1995.tb13791.x"},{"key":"bibr5-0300060520961684","first-page":"9","volume":"74","author":"Betterle C","year":"2003","journal-title":"Acta Biomed"},{"key":"bibr6-0300060520961684","doi-asserted-by":"publisher","DOI":"10.14310\/horm.2002.11142"},{"key":"bibr7-0300060520961684","doi-asserted-by":"publisher","DOI":"10.1210\/edrv.23.3.0466"},{"key":"bibr8-0300060520961684","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-5448.2009.00622.x"},{"key":"bibr9-0300060520961684","first-page":"327","volume":"150","author":"Beressi N","year":"1999","journal-title":"Ann Med Interne (Paris)"},{"key":"bibr10-0300060520961684","doi-asserted-by":"publisher","DOI":"10.1210\/er.2004-0011"},{"key":"bibr11-0300060520961684","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.1994.tb03023.x"},{"key":"bibr12-0300060520961684","first-page":"247","volume":"6","author":"Papathanasiou A","year":"2007","journal-title":"Hormones (Athens)"},{"key":"bibr13-0300060520961684","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200010263431707"},{"key":"bibr14-0300060520961684","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-29-6-777"},{"key":"bibr15-0300060520961684","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-26-11-1257"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300060520961684","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0300060520961684","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300060520961684","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:46:19Z","timestamp":1777459579000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0300060520961684"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10]]},"references-count":15,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2020,10]]}},"alternative-id":["10.1177\/0300060520961684"],"URL":"https:\/\/doi.org\/10.1177\/0300060520961684","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10]]},"article-number":"0300060520961684"}}