{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T14:58:40Z","timestamp":1790089120897,"version":"4.0.1"},"reference-count":27,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"The National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["81701456"],"award-info":[{"award-number":["81701456"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100012245","name":"Science and Technology Program of Guangdong","doi-asserted-by":"crossref","award":["2016A020218002"],"award-info":[{"award-number":["2016A020218002"]}],"id":[{"id":"10.13039\/501100012245","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The study aimed to evaluate cervical ripening by measuring cervical collagen levels in non-pregnant women, women with a normal pregnancy, and postpartum women by light-induced fluorescence (LIF).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Cervical collagen content in normal pregnant women (n\u2009=\u2009165) at various times of gestation was measured by LIF with a collascope, which is specifically designed to measure fluorescence of collagen. Cervical LIF in non-pregnant women (n\u2009=\u200912) and postpartum women (n\u2009=\u200914) was also detected. The demographic characteristics of women at various times were recorded. The Bishop score at 40 to 41 gestational weeks (n\u2009=\u200937) before the onset of labor was analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Cervical LIF values progressively declined from the non-pregnant state to late gestation (R\u2009=\u2009\u22120.836) and reached their lowest levels during parturition and then increased at postpartum. LIF values and the Bishop score were significantly negatively correlated (R\u2009=\u2009\u22120.83). In patients with a Bishop score \u22656, the first stage of labor was shortened with a decrease in LIF values (R\u2009=\u20090.718).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Cervical collagen levels as measured by LIF could be a useful method for evaluating cervical maturity.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0300060520964006","type":"journal-article","created":{"date-parts":[[2020,11,18]],"date-time":"2020-11-18T01:43:26Z","timestamp":1605663806000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Evaluation of cervical maturity by cervical collagen measurement using light-induced fluorescence (LIF) during pregnancy"],"prefix":"10.1177","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0421-9272","authenticated-orcid":false,"given":"Zheng","family":"Zheng","sequence":"first","affiliation":[{"name":"Department of Obstetrics, First Affiliated Hospital of Jinan University, Guangzhou, China; Guangzhou Women and Children's Medical Centre, Guangzhou Medical University, Guangzhou, China"},{"name":"Department of Obstetrics, Preterm Birth Prevention and Treatment Research Unit, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaodan","family":"Di","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Preterm Birth Prevention and Treatment Research Unit, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lele","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Preterm Birth Prevention and Treatment Research Unit, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weijuan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Preterm Birth Prevention and Treatment Research Unit, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Feng","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Preterm Birth Prevention and Treatment Research Unit, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shao-Qing","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Preterm Birth Prevention and Treatment Research Unit, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert E","family":"Garfield","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Preterm Birth Prevention and Treatment Research Unit, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1197-5343","authenticated-orcid":false,"given":"Huishu","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, First Affiliated Hospital of Jinan University, Guangzhou, China; Guangzhou Women and Children's Medical Centre, Guangzhou Medical University, Guangzhou, China"},{"name":"Department of Obstetrics, Preterm Birth Prevention and Treatment Research Unit, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,11,17]]},"reference":[{"key":"bibr1-0300060520964006","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1959.sp006304"},{"key":"bibr2-0300060520964006","doi-asserted-by":"publisher","DOI":"10.1097\/00003081-198303000-00005"},{"key":"bibr3-0300060520964006","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(83)90446-5"},{"key":"bibr4-0300060520964006","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(92)91619-L"},{"key":"bibr5-0300060520964006","doi-asserted-by":"publisher","DOI":"10.1097\/00003081-199506000-00009"},{"key":"bibr6-0300060520964006","doi-asserted-by":"publisher","DOI":"10.1055\/s-2006-956777"},{"key":"bibr7-0300060520964006","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.116.142844"},{"key":"bibr8-0300060520964006","doi-asserted-by":"publisher","DOI":"10.1016\/j.tem.2010.01.011"},{"key":"bibr9-0300060520964006","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/12.10.2093"},{"key":"bibr10-0300060520964006","doi-asserted-by":"publisher","DOI":"10.1016\/0090-6980(93)90114-M"},{"key":"bibr11-0300060520964006","doi-asserted-by":"publisher","DOI":"10.1093\/molehr\/6.4.382"},{"key":"bibr12-0300060520964006","doi-asserted-by":"publisher","DOI":"10.1007\/BF00207713"},{"key":"bibr13-0300060520964006","doi-asserted-by":"publisher","DOI":"10.1053\/j.semperi.2017.08.006"},{"key":"bibr14-0300060520964006","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(95)90648-7"},{"key":"bibr15-0300060520964006","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2005.00596.x"},{"key":"bibr16-0300060520964006","doi-asserted-by":"publisher","DOI":"10.1515\/JPM.1999.026"},{"key":"bibr17-0300060520964006","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2012.05.015"},{"key":"bibr18-0300060520964006","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/4.5.673"},{"key":"bibr19-0300060520964006","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2005.03.006"},{"key":"bibr20-0300060520964006","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2011.02.048"},{"key":"bibr21-0300060520964006","doi-asserted-by":"publisher","DOI":"10.1515\/JPM.1999.026"},{"key":"bibr22-0300060520964006","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2003.94"},{"key":"bibr23-0300060520964006","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1093\/biolre\/ioz109","volume":"101","author":"Yang J","year":"2019","journal-title":"Biol Reprod"},{"key":"bibr24-0300060520964006","first-page":"266","volume":"24","author":"Bishop EH.","year":"1964","journal-title":"Obstetrics & Gynecology"},{"key":"bibr25-0300060520964006","doi-asserted-by":"publisher","DOI":"10.1097\/00006250-198605000-00006"},{"key":"bibr26-0300060520964006","first-page":"875","volume":"102","author":"American College of Obstetricians and Gynecologists","year":"2003","journal-title":"Obstet Gynecol"},{"issue":"2","key":"bibr27-0300060520964006","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1097\/AOG.0b013e3181b48ef5","volume":"114","author":"ACOG Committee on Practice Bulletins \u2013 Obstetrics.","year":"2009","journal-title":"Obstet Gynecol"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300060520964006","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0300060520964006","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300060520964006","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:51:18Z","timestamp":1777459878000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0300060520964006"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11]]},"references-count":27,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2020,11]]}},"alternative-id":["10.1177\/0300060520964006"],"URL":"https:\/\/doi.org\/10.1177\/0300060520964006","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,11]]},"article-number":"0300060520964006"}}