{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T08:43:59Z","timestamp":1778057039669,"version":"3.51.4"},"reference-count":17,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>We explored the relationship between enuresis and obstructive sleep apnea\u2013hypopnea syndrome (OSAHS) in children and influencing factors of enuresis with OSAHS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We recruited 196 children \u22655 years old from the otolaryngology outpatient department, who experienced snoring and underwent nasopharynx lateral radiography and in-laboratory polysomnography. We analyzed correlations between the apnea\u2013hypopnea index (AHI) and lowest oxygen saturation (L-SaO2) with age, body mass index (BMI), tonsil size, and adenoidal\u2013nasopharyngeal (A\/N) ratio using the Pearson correlation test. Differences in severe OSAHS prevalence, age, AHI, L-SaO2, tonsil size, and A\/N ratio between children with and without enuresis were assessed using the chi-square test and t-test. Risk factors of enuresis were analyzed using logistic regression. Follow-up was conducted to assess remission in children with enuresis after adenotonsillectomy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>BMI, tonsil size, and A\/N ratio were correlated with AHI and L-SaO2. Severe OSAHS prevalence, AHI, tonsil size, and A\/N ratio were higher and L-SaO2 were lower in children with enuresis. Logistic regression showed that BMI, AHI, tonsil size, and sleep apnea were risk factors for enuresis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our study findings showed that enuresis was associated with OSAHS in children. Adenotonsillectomy may improve the symptoms of enuresis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0300060520977407","type":"journal-article","created":{"date-parts":[[2020,12,10]],"date-time":"2020-12-10T13:17:54Z","timestamp":1607606274000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["Relationship between enuresis and obstructive sleep apnea\u2013hypopnea syndrome in children"],"prefix":"10.1177","volume":"48","author":[{"given":"Chen","family":"Sun","sequence":"first","affiliation":[{"name":"Department of ENT, Children\u2019s Hospital of Nanjing Medical University, Nanjing, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yingpeng","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of ENT, Children\u2019s Hospital of Nanjing Medical University, Nanjing, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chenxi","family":"Luo","sequence":"additional","affiliation":[{"name":"Department of ENT, Children\u2019s Hospital of Nanjing Medical University, Nanjing, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2643-685X","authenticated-orcid":false,"given":"Qi","family":"Li","sequence":"additional","affiliation":[{"name":"Department of ENT, Children\u2019s Hospital of Nanjing Medical University, Nanjing, Jiangsu, China"},{"name":"Medical School of Nanjing University, Nanjing, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,12,8]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2010.134858"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2011.01.036"},{"key":"e_1_3_3_4_2","doi-asserted-by":"crossref","unstructured":"Kuwertz-Br\u00f6king E Von Gontard A. Clinical management of nocturnal enuresis. Pediatr Nephrol 2017.","DOI":"10.1026\/02934-000"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/pr.2014.137"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-017-3750-0"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2003.tb02469.x"},{"key":"e_1_3_3_8_2","article-title":"Introduction to the special issue: \u201cFocus on pediatric nephrology\u201d.","volume":"33","author":"Chimenz R.","year":"2019","unstructured":"Chimenz R. Introduction to the special issue: \u201cFocus on pediatric nephrology\u201d. J Biol Regul Homeost Agents 2019; 33: 1.","journal-title":"J Biol Regul Homeost Agents"},{"key":"e_1_3_3_9_2","first-page":"729","article-title":"[Chinese guideline for the diagnosis and treatment of childhood obstructive sleep apnea (2020)]","volume":"55","author":"Working Group of Chinese Guideline for the Diagnosis and Treatment of Childhood OSA, Subspecialty Group of Pediatrics, Society of Otorhinolaryngology Head and Neck Surgery, Chinese Medical Association, Subspecialty Group of Respiratory Diseases, Society of Pediatrics, Chinese Medical Association","year":"2020","unstructured":"Working Group of Chinese Guideline for the Diagnosis and Treatment of Childhood OSA, Subspecialty Group of Pediatrics, Society of Otorhinolaryngology Head and Neck Surgery, Chinese Medical Association, Subspecialty Group of Respiratory Diseases, Society of Pediatrics, Chinese Medical Associationet\u00a0al. [Chinese guideline for the diagnosis and treatment of childhood obstructive sleep apnea (2020)]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2020; 55: 729\u2013747.","journal-title":"Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2012-1672"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0000000000003752"},{"key":"e_1_3_3_12_2","first-page":"83","article-title":"Draft guidelines for the diagnosis and treatment of obstructive sleep apnea hypopnea syndrome in children (Urumqi","volume":"42","author":"Editorial Board of Chinese Journal of Otolaryngology Head and Neck Surgery","year":"2007","unstructured":"Editorial Board of Chinese Journal of Otolaryngology Head and Neck Surgery. Draft guidelines for the diagnosis and treatment of obstructive sleep apnea hypopnea syndrome in children (Urumqi). Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2007; 42: 83\u201384.","journal-title":"Chinese Journal of Otorhinolaryngology Head and Neck Surgery"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-012-1687-7"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2005.11.011"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrurol.2015.266"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-011-1762-8"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2008.01.171"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2017.11.033"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300060520977407","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0300060520977407","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300060520977407","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:44:06Z","timestamp":1777459446000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0300060520977407"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12]]},"references-count":17,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2020,12]]}},"alternative-id":["10.1177\/0300060520977407"],"URL":"https:\/\/doi.org\/10.1177\/0300060520977407","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,12]]},"article-number":"0300060520977407"}}