{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T18:32:15Z","timestamp":1792089135062,"version":"4.4.0"},"reference-count":21,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Sichuan Science and Technology Program","award":["2019YJ0577"],"award-info":[{"award-number":["2019YJ0577"]}]},{"name":"Science and Technology Project of Sichuan Overseas Students","award":["2019-58"],"award-info":[{"award-number":["2019-58"]}]},{"name":"Science and Technology Project of the Health Planning Committee of Sichuan","award":["19PJ126"],"award-info":[{"award-number":["19PJ126"]}]},{"name":"Science and Technology Project of the Health Planning Committee of Sichuan","award":["20ZD011"],"award-info":[{"award-number":["20ZD011"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:p>Heart surgery in patients from high-altitude areas is more challenging than usual. Few studies have been published on this issue, and none of them have discussed the effect of an altitude change (from high to low altitude) on a patient\u2019s physiology or its effects on a patient\u2019s perioperative management. Here, we present the case of a 46-year-old man who was a long-time resident of Tibetan area in Sichuan (altitude &gt;3000 m) who underwent Stanford type A aortic dissection emergency surgery on the plain. Anesthetic management occurred through monitoring of the bispectral index (BIS) and transesophageal echocardiography (TEE), and we used a relatively loose fluid hydration strategy. The surgery was performed using cardiopulmonary bypass (CPB), deep hypothermia (DH), and selective antegrade cerebral perfusion. The most prominent anesthesia challenges for these patients are physiological changes due to habitation in an high-altitude environment (chronic hypoxemia), which can cause hyperhemoglobinemia, polycythemia, hypercoagulable blood, and even pulmonary hypertension, cor pulmonale, or congestive heart failure. Optimized perioperative management and close cooperation among the entire cardiac medical team were the key factors in the successful management of this rare case.<\/jats:p>","DOI":"10.1177\/0300060520979871","type":"journal-article","created":{"date-parts":[[2020,12,22]],"date-time":"2020-12-22T03:04:49Z","timestamp":1608606289000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Anesthesia of a high-altitude area inhabitant who underwent aortic dissection emergency surgery in a low-altitude area"],"prefix":"10.1177","volume":"48","author":[{"given":"Huan","family":"Zheng","sequence":"first","affiliation":[{"name":"Department of Anesthesiology, Sichuan Academy of Medical Sciences &amp; Sichuan Provincial People\u2019s Hospital, University of Electronic Science and Technology of China, Chengdu, China"},{"name":"Chinese Academy of Sciences Sichuan Translational Medicine Research Hospital, Chengdu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin-Chuan","family":"Wei","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Sichuan Academy of Medical Sciences &amp; Sichuan Provincial People\u2019s Hospital, University of Electronic Science and Technology of China, Chengdu, China"},{"name":"Chinese Academy of Sciences Sichuan Translational Medicine Research Hospital, Chengdu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Yu","sequence":"additional","affiliation":[{"name":"Chinese Academy of Sciences Sichuan Translational Medicine Research Hospital, Chengdu, China"},{"name":"Department of Cardiovascular Surgery, Sichuan Academy of Medical Sciences &amp; Sichuan Provincial People\u2019s Hospital, University of Electronic Science and Technology of China, Chengdu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8647-1011","authenticated-orcid":false,"given":"Qian","family":"Lei","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Sichuan Academy of Medical Sciences &amp; Sichuan Provincial People\u2019s Hospital, University of Electronic Science and Technology of China, Chengdu, China"},{"name":"Chinese Academy of Sciences Sichuan Translational Medicine Research Hospital, Chengdu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,12,22]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)13591-X"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00540-009-0787-7"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12871-015-0104-y"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1177\/0300060516687230"},{"key":"e_1_3_2_6_2","first-page":"1288","article-title":"Perioperative safety of Tibetan children with congenital heart disease undergoing cardiac surgery and anesthesia in low-altitude area","volume":"42","author":"Pan Y","year":"2017","unstructured":"Pan Y, Niu J, Qin G, et\u00a0al. Perioperative safety of Tibetan children with congenital heart disease undergoing cardiac surgery and anesthesia in low-altitude area. Zhong Nan Da Xue Bao Yi Xue Ban 2017; 42: 1288\u20131292. DOI: 10.11817\/j.issn.1672-7347.2017.11.008.","journal-title":"Zhong Nan Da Xue Bao Yi Xue Ban"},{"key":"e_1_3_2_7_2","first-page":"399","article-title":"A case report of cardiac arrest after cardiac surgery in overweight pediatric from high altitude area","author":"Li Q","year":"2003","unstructured":"Li Q, Yu H, Liu B, et\u00a0al. A case report of cardiac arrest after cardiac surgery in overweight pediatric from high altitude area. 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