{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T13:05:27Z","timestamp":1777727127080,"version":"3.51.4"},"reference-count":26,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study analyzed the possible effects of intratympanic steroid (ITS) therapy in the symptomatic treatment of vertigo attacks in patients with M\u00e9ni\u00e8re\u2019s disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Thirty-five patients treated with ITS (dexamethasone) plus betahistine (Group A) and 35 patients treated with betahistine alone (Group B) were enrolled in this investigation. Complaints were analyzed using medical records and vertigo diaries. Statistical analysis was conducted using IBM SPSS V24 software.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Based on the analysis, there were no significant differences in baseline features between the two groups. When the occurrence of vertigo attacks was compared using the Kaplan\u2013Meier method, no significant difference was detected between Groups A and B (odds ratio [OR]\u2009=\u20091.051, 95% confidence interval [CI]\u2009=\u20090.965\u20131.067; p\u2009=\u20090.972). In addition, no difference in the incidence of vertigo attacks was noted in group A between the periods of treatment with betahistine alone and betahistine plus ITS when the groups were analyzed via logistic regression (OR\u2009=\u20091.07, 95% CI\u2009=\u20090.065\u20131.467; p\u2009=\u20090.614).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>It can be concluded that the addition of ITS therapy to betahistine did not improve outcomes in patients with M\u00e9ni\u00e8re\u2019s disease. Further prospective studies should be conducted to analyze the results in a more detailed manner.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0300060520985647","type":"journal-article","created":{"date-parts":[[2021,4,13]],"date-time":"2021-04-13T01:11:22Z","timestamp":1618276282000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Effectiveness of intratympanic dexamethasone for the treatment of vertigo attacks in patients with M\u00e9ni\u00e8re\u2019s disease compared with betahistine pharmacotherapy"],"prefix":"10.1177","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4417-5166","authenticated-orcid":false,"given":"Andr\u00e1s","family":"Moln\u00e1r","sequence":"first","affiliation":[{"name":"Semmelweis University, Department of Otolaryngology and Head and Neck Surgery, Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3024-6197","authenticated-orcid":false,"given":"Stefani","family":"Maihoub","sequence":"additional","affiliation":[{"name":"Semmelweis University, Department of Otolaryngology and Head and Neck Surgery, Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L\u00e1szl\u00f3","family":"Tam\u00e1s","sequence":"additional","affiliation":[{"name":"Semmelweis University, Department of Otolaryngology and Head and Neck Surgery, Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c1gnes","family":"Szirmai","sequence":"additional","affiliation":[{"name":"Semmelweis University, Department of Otolaryngology and Head and Neck Surgery, Budapest, 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