{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T01:47:17Z","timestamp":1792633637225,"version":"4.5.0"},"reference-count":28,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To explore the risk factors associated with esophagojejunal anastomotic leakage (EJAL) after curative total gastrectomy combined with D2 lymph node dissection for gastric cancer.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We reviewed the data for 390 consecutive patients undergoing Roux-en-Y esophagojejunostomy reconstruction after total gastrectomy. Multivariate analysis was performed using a logistic regression model to identify the independent risk factors for EJAL.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of the 390 patients enrolled in this study, EJAL occurred in 10 patients (2.6%), and one patient (1\/10) with EJAL died. Univariate analysis identified age, alcohol consumption, pulmonary insufficiency, and intraoperative blood loss as risk factors for EJAL. Of these four risk factors, age and alcohol consumption were retained as independent risk factors by multivariate analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Surgeons should be very careful regarding anastomotic leakage after esophagojejunal anastomosis, perioperatively, especially in patients with advanced age and a history of alcohol consumption. Pulmonary insufficiency and intraoperative blood loss, although not identified as independent risk factors, should also be considered.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/03000605211000883","type":"journal-article","created":{"date-parts":[[2024,10,4]],"date-time":"2024-10-04T01:44:01Z","timestamp":1728006241000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":17,"title":["Risk factors for esophagojejunal anastomotic leakage after curative total gastrectomy combined with D2 lymph node dissection for gastric cancer"],"prefix":"10.1177","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6463-7594","authenticated-orcid":false,"given":"Jiadi","family":"Xing","sequence":"first","affiliation":[{"name":"Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Gastrointestinal Surgery IV, Peking University Cancer Hospital and Institute, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maoxing","family":"Liu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Gastrointestinal Surgery IV, Peking University Cancer Hospital and Institute, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyu","family":"Qi","sequence":"additional","affiliation":[{"name":"Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Gastrointestinal Surgery IV, Peking University Cancer Hospital and Institute, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianhong","family":"Yu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Gastrointestinal Surgery IV, Peking University Cancer Hospital and Institute, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingcong","family":"Fan","sequence":"additional","affiliation":[{"name":"Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Gastrointestinal Surgery IV, Peking University Cancer Hospital and Institute, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai","family":"Xu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Gastrointestinal Surgery IV, Peking University Cancer Hospital and Institute, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pin","family":"Gao","sequence":"additional","affiliation":[{"name":"Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Gastrointestinal Surgery IV, Peking University Cancer Hospital and Institute, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei","family":"Tan","sequence":"additional","affiliation":[{"name":"Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Gastrointestinal Surgery IV, Peking University Cancer Hospital and Institute, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhendan","family":"Yao","sequence":"additional","affiliation":[{"name":"Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Gastrointestinal Surgery IV, Peking University Cancer Hospital and Institute, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Gastrointestinal Surgery IV, Peking University Cancer Hospital and Institute, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Yang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Gastrointestinal Surgery IV, Peking University Cancer Hospital and Institute, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenghai","family":"Zhang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Gastrointestinal Surgery IV, Peking University Cancer Hospital and Institute, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6463-7594","authenticated-orcid":false,"given":"Ming","family":"Cui","sequence":"additional","affiliation":[{"name":"Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Gastrointestinal Surgery IV, Peking University Cancer Hospital and Institute, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangqian","family":"Su","sequence":"additional","affiliation":[{"name":"Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Gastrointestinal Surgery IV, Peking University Cancer Hospital and Institute, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,3,18]]},"reference":[{"key":"bibr1-03000605211000883","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.7038"},{"key":"bibr2-03000605211000883","doi-asserted-by":"publisher","DOI":"10.1159\/000102100"},{"key":"bibr3-03000605211000883","first-page":"1509","volume":"44","author":"Isozaki H","year":"1997","journal-title":"Hepatogastroenterology"},{"key":"bibr4-03000605211000883","first-page":"613","volume":"51","author":"Ichikawa D","year":"2004","journal-title":"Hepatogastroenterology"},{"key":"bibr5-03000605211000883","doi-asserted-by":"publisher","DOI":"10.1007\/s00423-005-0575-2"},{"key":"bibr6-03000605211000883","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-012-1559-3"},{"key":"bibr7-03000605211000883","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-012-1932-4"},{"key":"bibr8-03000605211000883","first-page":"1355","volume":"17","author":"Zilling T","year":"1997","journal-title":"Anticancer Res"},{"key":"bibr9-03000605211000883","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2016.11.022"},{"key":"bibr10-03000605211000883","doi-asserted-by":"publisher","DOI":"10.5578\/turkjsurg.4117"},{"key":"bibr11-03000605211000883","volume-title":"International Union Against Cancer (UICC). TNM Classification of Malignant Tumours","author":"Sobin LH","year":"2010","edition":"7"},{"key":"bibr12-03000605211000883","unstructured":"U.S. Department of Agriculture and U.S. Department of Health and Human Services. In:\n                      Dietary Guidelines for Americans\n                      . 7\n                      th\n                      ed. Washington, DC: U.S. Government Printing Office, 2010."},{"key":"bibr13-03000605211000883","doi-asserted-by":"publisher","DOI":"10.1007\/s00595-018-1726-8"},{"key":"bibr14-03000605211000883","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v21.i32.9656"},{"key":"bibr15-03000605211000883","first-page":"218","volume":"58","author":"Tsou CC","year":"2011","journal-title":"Hepatogastroenterology"},{"key":"bibr16-03000605211000883","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.138.1.34"},{"key":"bibr17-03000605211000883","doi-asserted-by":"publisher","DOI":"10.1159\/000078381"},{"key":"bibr18-03000605211000883","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2005.02.002"},{"key":"bibr19-03000605211000883","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v20.i2.607"},{"key":"bibr20-03000605211000883","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-012-2714-7"},{"key":"bibr21-03000605211000883","doi-asserted-by":"publisher","DOI":"10.1080\/0284186X.2016.1267872"},{"key":"bibr22-03000605211000883","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpg.2017.10.005"},{"key":"bibr23-03000605211000883","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2168.1998.00615.x"},{"key":"bibr24-03000605211000883","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2168.1999.01165.x"},{"key":"bibr25-03000605211000883","doi-asserted-by":"publisher","DOI":"10.1080\/02841860510029707"},{"key":"bibr26-03000605211000883","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(92)91405-W"},{"key":"bibr27-03000605211000883","doi-asserted-by":"publisher","DOI":"10.1007\/BF02554788"},{"key":"bibr28-03000605211000883","first-page":"485","volume":"92","author":"Gloria L","year":"1997","journal-title":"Am J Gastroenterol"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03000605211000883","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/03000605211000883","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03000605211000883","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:48:19Z","timestamp":1777459699000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/03000605211000883"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3]]},"references-count":28,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["10.1177\/03000605211000883"],"URL":"https:\/\/doi.org\/10.1177\/03000605211000883","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3]]},"article-number":"03000605211000883"}}