{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T13:08:35Z","timestamp":1777727315483,"version":"3.51.4"},"reference-count":12,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This prospective study aimed to assess the effect of short-acting gonadotropin-releasing hormone agonist (GnRHa) administration on pregnancy outcomes in frozen\u2013thawed embryo transfer (FET) cycles.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients who planned to have FET in Peking Union Medical College Hospital (China) were recruited for this study and randomly assigned into two groups. Patients in the experimental group (n\u2009=\u2009460) received triptorelin acetate on the day of embryo transfer along with routine luteal support. Patients in the control group (n\u2009=\u2009433) only received luteal support. One dose (0.1\u2009mg) of a short-acting GnRHa was administered on the day of blastocyte transfer. The rates for clinical pregnancy, biochemical pregnancy, implantation, miscarriage, and ectopic pregnancy were compared between the groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>There were no significant differences in the number and quality of blastocytes transferred between the two groups. In the experimental and control groups, the clinical pregnancy rate was 56.3% and 50.58%, the biochemical pregnancy rate was 15.78% and 18.94%, and the median implantation rate was 39.98% and 38.01%, respectively, with no significant difference between the groups. Biochemical pregnancy and abortion and the ectopic pregnancy rate were not significantly different between the two groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In FET cycles, a GnRHa does not affect the pregnancy outcome.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/03000605211012247","type":"journal-article","created":{"date-parts":[[2021,5,9]],"date-time":"2021-05-09T02:30:05Z","timestamp":1620527405000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Single-dose administration of a short-acting gonadotropin-releasing hormone agonist does not affect cycle outcome in frozen\u2013thawed embryo transfer cycles"],"prefix":"10.1177","volume":"49","author":[{"given":"Hanbi","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xian","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, the Central Hospital of Loudi, Hunan Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Orhan","family":"Bukulmez","sequence":"additional","affiliation":[{"name":"Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, Texas, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6414-4992","authenticated-orcid":false,"given":"Chengyan","family":"Deng","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qi","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuanzheng","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhengyi","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingran","family":"Zhen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xue","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meizhi","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,5,4]]},"reference":[{"key":"bibr1-03000605211012247","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmv059"},{"key":"bibr2-03000605211012247","doi-asserted-by":"publisher","DOI":"10.1080\/09513590.2016.1193141"},{"key":"bibr3-03000605211012247","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dem421"},{"key":"bibr4-03000605211012247","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deh235"},{"key":"bibr5-03000605211012247","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deh830"},{"key":"bibr6-03000605211012247","unstructured":"Hugues JN, Cedrin-Durnerin I, Bstandig B, et\u00a0al. Administration of gonadotropin-releasing hormone agonist during the luteal phase of the GnRH-antagonist IVF cycles. In: the\n                      22nd Annual Meeting of the Society of Human Reproduction and Embryology\n                      , Prague, 18\u201321 June 2006, paper no. i5."},{"key":"bibr7-03000605211012247","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/del072"},{"key":"bibr8-03000605211012247","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/del173"},{"key":"bibr9-03000605211012247","first-page":"120","volume":"37","author":"Li TT","year":"2016","journal-title":"J Sun Yat-Sen University"},{"key":"bibr10-03000605211012247","unstructured":"Chinese Medical Association. Clinical Guidelines, booklet of assisted reproductive technology and sperm bank. \nBeijing: \nPeople's Medical Publishing House, 2009, pp.157\u2013159."},{"key":"bibr11-03000605211012247","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dep343"},{"key":"bibr12-03000605211012247","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/del321"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03000605211012247","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/03000605211012247","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03000605211012247","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:49:07Z","timestamp":1777459747000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/03000605211012247"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5]]},"references-count":12,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2021,5]]}},"alternative-id":["10.1177\/03000605211012247"],"URL":"https:\/\/doi.org\/10.1177\/03000605211012247","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5]]},"article-number":"03000605211012247"}}