{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T14:23:55Z","timestamp":1793283835666,"version":"4.5.0"},"reference-count":34,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003453","name":"Natural Science Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2018A030313640"],"award-info":[{"award-number":["2018A030313640"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003453","name":"Natural Science Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2019A1515012176"],"award-info":[{"award-number":["2019A1515012176"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Shanghai Wang Zhengguo trauma medical development foundation","award":["2017KJB-GK-001"],"award-info":[{"award-number":["2017KJB-GK-001"]}]},{"name":"Clinical Research Projects of President Foundation of Nanfang Hospital, Southern Medical University","award":["2020CR008"],"award-info":[{"award-number":["2020CR008"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate the clinical efficacy of free flap transplantation combined with Ilizarov bone transport in the treatment of severe composite tibial and soft tissue defects.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively analyzed the clinical data of 40 patients with severe composite tibial and soft tissue defects who underwent free flap transplantation combined with Ilizarov bone transport. The clinical efficacy was evaluated according to the following criteria: success rate of wound repair by free flap transplantation, incidence or recurrence rate of deep infection, healing rate of bone defects and external fixation index, incidence of complications, and functional score of affected extremities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>All infections were generally well controlled by radical debridement and negative-pressure therapy, and all 40 patients\u2019 wounds healed after repair and reconstruction of the tibia and soft tissues. Postoperative complications were alleviated by active treatment. The mean external fixation time was 12.83\u2009\u00b1\u20092.85 months, and the external fixation index was 1.55 m\/cm. According to the Association for the Study and Application of Methods of Ilizarov (ASAMI) score, an excellent or good functional outcome was attained in 85% of patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Free flap transplantation combined with Ilizarov bone transport is an effective treatment for severe composite tibial and soft tissue defects.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/03000605211017618","type":"journal-article","created":{"date-parts":[[2021,5,29]],"date-time":"2021-05-29T16:06:18Z","timestamp":1622304378000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["Free flap transplantation combined with Ilizarov bone transport for the treatment of severe composite tibial and soft tissue defects"],"prefix":"10.1177","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4703-7180","authenticated-orcid":false,"given":"Runguang","family":"Li","sequence":"first","affiliation":[{"name":"Department of Foot and Ankle Surgery, Center for Orthopaedic Surgery, the Third Affiliated Hospital of Southern Medical University, Guangzhou, China"},{"name":"Orthopaedic Hospital of Guangdong Province, Guangzhou, China"},{"name":"Academy of Orthopaedics, Guangdong Province, Guangzhou, China"},{"name":"Guangdong Provincial Key Laboratory of Bone and Joint Degenerative Diseases, Guangzhou, China"},{"name":"Department of Orthopedics, Linzhi People\u2019s Hospital, Linzhi, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Canjun","family":"Zeng","sequence":"additional","affiliation":[{"name":"Department of Foot and Ankle Surgery, Center for Orthopaedic Surgery, the Third Affiliated Hospital of Southern Medical University, Guangzhou, China"},{"name":"Orthopaedic 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and Ankle Surgery, Center for Orthopaedic Surgery, the Third Affiliated Hospital of Southern Medical University, Guangzhou, China"},{"name":"Orthopaedic Hospital of Guangdong Province, Guangzhou, China"},{"name":"Academy of Orthopaedics, Guangdong Province, Guangzhou, China"},{"name":"Guangdong Provincial Key Laboratory of Bone and Joint Degenerative Diseases, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gao-hong","family":"Ren","sequence":"additional","affiliation":[{"name":"Division of Orthopaedics and Traumatology, Department of Orthopaedics, Nanfang Hospital, Southern Medical University, Guangzhou, China"},{"name":"Key Laboratory of Bone and Cartilage Regenerative Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, 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