{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T13:01:34Z","timestamp":1777726894226,"version":"3.51.4"},"reference-count":15,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Key Scientific Research projects of Colleges and Universities in Henan Province","award":["19A320091"],"award-info":[{"award-number":["19A320091"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:p>A 56-year-old woman with a history of diabetes mellitus presented with high fever but no abdominal pain. An abdominal computed tomography scan showed a large liver abscess. Hypervirulent, string test-positive, rmpA\/ ampA2-, and iutA-positive Klebsiella pneumoniae was rapidly identified from drainage fluid of the liver abscess using metagenomic next-generation sequencing (mNGS). After intravenous antibiotic therapy and drainage of the abscess, the patient\u2019s condition resolved. This case report highlights the value of mNGS in rapidly and accurately identifying a pathogenic microorganism, which helps reduce the incidence of antimicrobial resistance and enables the targeted use of antibiotics.<\/jats:p>","DOI":"10.1177\/03000605211032793","type":"journal-article","created":{"date-parts":[[2021,7,28]],"date-time":"2021-07-28T01:58:55Z","timestamp":1627437535000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["A case report of pyogenic liver abscess caused by hypervirulent\n                    <i>Klebsiella pneumoniae<\/i>\n                    diagnosed by metagenomic next-generation sequencing"],"prefix":"10.1177","volume":"49","author":[{"given":"Jiafeng","family":"Xie","sequence":"first","affiliation":[{"name":"The Emergency Intensive Care Unit, the First Affiliated Hospital of Zhengzhou University, Henan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0280-3232","authenticated-orcid":false,"given":"Zhiqiang","family":"Zhu","sequence":"additional","affiliation":[{"name":"The Emergency Intensive Care Unit, the First Affiliated Hospital of Zhengzhou University, Henan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,7,27]]},"reference":[{"key":"bibr1-03000605211032793","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1989.00390060171048"},{"key":"bibr2-03000605211032793","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(12)70205-0"},{"key":"bibr3-03000605211032793","doi-asserted-by":"publisher","DOI":"10.4161\/viru.22718"},{"key":"bibr4-03000605211032793","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(13)70068-9"},{"key":"bibr5-03000605211032793","doi-asserted-by":"publisher","DOI":"10.1111\/head.12246"},{"key":"bibr6-03000605211032793","doi-asserted-by":"publisher","DOI":"10.2147\/IDR.S247341"},{"key":"bibr7-03000605211032793","doi-asserted-by":"publisher","DOI":"10.1111\/joim.13007"},{"key":"bibr8-03000605211032793","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cit675"},{"key":"bibr9-03000605211032793","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2009.614"},{"key":"bibr10-03000605211032793","doi-asserted-by":"publisher","DOI":"10.1186\/s12941-018-0302-9"},{"key":"bibr11-03000605211032793","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2005-2749"},{"key":"bibr12-03000605211032793","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.162.9.1021"},{"key":"bibr13-03000605211032793","doi-asserted-by":"publisher","DOI":"10.1016\/j.jiac.2018.07.006"},{"key":"bibr14-03000605211032793","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.01888-15"},{"key":"bibr15-03000605211032793","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02664-15"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03000605211032793","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/03000605211032793","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03000605211032793","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:48:05Z","timestamp":1777459685000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/03000605211032793"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7]]},"references-count":15,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2021,7]]}},"alternative-id":["10.1177\/03000605211032793"],"URL":"https:\/\/doi.org\/10.1177\/03000605211032793","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,7]]},"article-number":"03000605211032793"}}