{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T13:00:30Z","timestamp":1777726830345,"version":"3.51.4"},"reference-count":18,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"This research is supported by the Foundation of Ministry of Health of Zhejiang Province, Hangzhou, China.","award":["(no.2018KY714)"],"award-info":[{"award-number":["(no.2018KY714)"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To compare the effectiveness of different approaches of neuraxial anesthesia in parturient women with obesity and pregnancy-induced hypertension (PIH) who undergo cesarean section (CS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively analyzed data from 108 parturient women with obesity and PIH who underwent CS. All women were divided into the following three groups according to the neuraxial anesthesia approach: spinal anesthesia (SA), epidural anesthesia (EA), and combined spinal\u2013epidural anesthesia (CSE). Clinical variables were compared.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The mean age of the patients was 27.3\u2009\u00b1\u20092.2 years. Women in the CSE group had a longer duration from puncture to surgery, smaller intraoperative change in mean arterial pressure, higher Apgar scores at 1 and 5 minutes, shorter surgery time, lower rates of nausea and vomiting, and lower rate of intraoperative hypotension compared with those in the SA and EA groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>CSE takes longer to administer in parturient women with obesity and PIH who undergo CS compared with those who have SA or EA. However, CSE has several advantages over SA or EA, including a shorter surgery time, more stable intraoperative mean arterial pressure, lower rates of nausea, vomiting, and intraoperative hypotension, and better Apgar scores at 1 and 5 minutes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/03000605211066433","type":"journal-article","created":{"date-parts":[[2021,12,21]],"date-time":"2021-12-21T16:55:15Z","timestamp":1640105715000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Comparison of three neuraxial anesthesia approaches in parturient women with obesity and pregnancy-induced hypertension who underwent cesarean section"],"prefix":"10.1177","volume":"49","author":[{"given":"Jie","family":"Li","sequence":"first","affiliation":[{"name":"Department of Obstetrics, Ningbo Women and Children\u2019s Hospital, Ningbo, Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"An-er","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Ningbo Women and Children\u2019s Hospital, Ningbo, Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9570-4665","authenticated-orcid":false,"given":"Ren","family":"Ye","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Ningbo Women and Children\u2019s Hospital, Ningbo, Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,12,21]]},"reference":[{"key":"bibr1-03000605211066433","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1505297"},{"key":"bibr2-03000605211066433","doi-asserted-by":"publisher","DOI":"10.3390\/jcm9061980"},{"key":"bibr3-03000605211066433","doi-asserted-by":"publisher","DOI":"10.3109\/10641955.2015.1115061"},{"key":"bibr4-03000605211066433","doi-asserted-by":"publisher","DOI":"10.4103\/0970-9185.119108"},{"key":"bibr5-03000605211066433","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0000000000002708"},{"key":"bibr6-03000605211066433","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijoa.2018.09.012"},{"key":"bibr7-03000605211066433","doi-asserted-by":"publisher","DOI":"10.1016\/j.amsu.2021.102383"},{"key":"bibr8-03000605211066433","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-6175.2001.00458.x"},{"key":"bibr9-03000605211066433","unstructured":"Obesity: preventing and managing the global epidemic. Report of a WHO consultation.\n                      World Health Organ Tech Rep Ser\n                      2000; 894: i\u2013xii, 1\u2013253."},{"key":"bibr10-03000605211066433","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-147-8-200710160-00010"},{"key":"bibr11-03000605211066433","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.6458"},{"key":"bibr12-03000605211066433","doi-asserted-by":"publisher","DOI":"10.4103\/aer.AER_69_20"},{"key":"bibr13-03000605211066433","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0236755"},{"key":"bibr14-03000605211066433","doi-asserted-by":"publisher","DOI":"10.5152\/TJAR.2020.70"},{"key":"bibr15-03000605211066433","doi-asserted-by":"publisher","DOI":"10.1016\/j.tjog.2014.03.006"},{"key":"bibr16-03000605211066433","doi-asserted-by":"publisher","DOI":"10.3906\/sag-1810-208"},{"key":"bibr17-03000605211066433","first-page":"e85115","volume":"9","author":"Nugroho AM","year":"2019","journal-title":"Anesth Pain Med"},{"key":"bibr18-03000605211066433","doi-asserted-by":"publisher","DOI":"10.1186\/s12884-021-03564-4"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03000605211066433","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/03000605211066433","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03000605211066433","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:47:55Z","timestamp":1777459675000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/03000605211066433"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12]]},"references-count":18,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["10.1177\/03000605211066433"],"URL":"https:\/\/doi.org\/10.1177\/03000605211066433","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12]]},"article-number":"03000605211066433"}}