{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T13:08:46Z","timestamp":1777727326914,"version":"3.51.4"},"reference-count":10,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:p>We report two suicidal cases of acute methyl ethyl ketone peroxide (MEKP) poisoning. A woman in her late 60s suffered from oral mucosal erosion, functional impairment of the heart, liver and other organs, pulmonary inflammation, elevated inflammatory markers, pleural effusion, hypoproteinemia and metabolic acidosis after oral administration of approximately 50\u2009mL of MEKP. After admission, the patient was administered hemoperfusion four times, 8\u2009mg of betamethasone for 6 days and symptomatic support. Hemoperfusion had an obvious effect on the treatment of oral MEKP poisoning. After discharge, the patient developed progressive dysphagia and secondary esophageal stenosis. Supplementary feeding was administered with a gastrostomy tube after the patient was completely unable to eat. A man in his mid-40s developed oropharyngeal mucosal erosion, bronchitis and esophageal wall thickening after oral administration of 40\u2009ml MEKP. After receiving total gastrointestinal dispersal, 80\u2009mg of methylprednisolone was administered for 7 days, and symptomatic supportive treatment was provided. Slight dysphagia was observed after discharge, and there was no major effect on the quality of life. Patients with acute oral MEKP poisoning should be followed up regularly to observe its long-term effects on digestive tract corrosion and stenosis.<\/jats:p>","DOI":"10.1177\/03000605211067694","type":"journal-article","created":{"date-parts":[[2022,1,7]],"date-time":"2022-01-07T10:26:37Z","timestamp":1641551197000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["A rare form of intoxication: acute methyl ethyl ketone peroxide poisoning"],"prefix":"10.1177","volume":"50","author":[{"given":"Cece","family":"Sun","sequence":"first","affiliation":[{"name":"Department of Poisoning and Occupational Diseases, Shandong University, Emergency Medicine, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tianzi","family":"Jian","sequence":"additional","affiliation":[{"name":"Department of Poisoning and Occupational Diseases, Shandong University, Emergency Medicine, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yaqian","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Poisoning and Occupational Diseases, Shandong University, Emergency Medicine, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siqi","family":"Cui","sequence":"additional","affiliation":[{"name":"Department of Poisoning and Occupational Diseases, Shandong University, Emergency Medicine, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China"},{"name":"School of Public Health, Cheeloo College of Medicine, Shandong University, Shandong University, Jinan, Shandong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Longke","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Poisoning and Occupational Diseases, Shandong University, Emergency Medicine, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China"},{"name":"School of Public Health, Cheeloo College of Medicine, Shandong University, Shandong University, Jinan, Shandong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guangcai","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Poisoning and Occupational Diseases, Shandong University, Emergency Medicine, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baotian","family":"Kan","sequence":"additional","affiliation":[{"name":"School of Nursing, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China"},{"name":"Department of Geriatric Medicine, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6587-7557","authenticated-orcid":false,"given":"Xiangdong","family":"Jian","sequence":"additional","affiliation":[{"name":"Department of Poisoning and Occupational Diseases, Shandong University, Emergency Medicine, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,1,7]]},"reference":[{"key":"bibr1-03000605211067694","doi-asserted-by":"publisher","DOI":"10.4172\/2161-0495.1000257"},{"key":"bibr2-03000605211067694","doi-asserted-by":"publisher","DOI":"10.1177\/0960327111407230"},{"key":"bibr3-03000605211067694","doi-asserted-by":"publisher","DOI":"10.1186\/s12995-015-0071-8"},{"key":"bibr4-03000605211067694","doi-asserted-by":"publisher","DOI":"10.1080\/15563650701232414"},{"key":"bibr5-03000605211067694","unstructured":"American Conference of Governmental Industrial Hygienists (ACGIH). Guide to occupational exposure values. 2005."},{"key":"bibr6-03000605211067694","doi-asserted-by":"publisher","DOI":"10.1177\/096032719000900315"},{"key":"bibr7-03000605211067694","doi-asserted-by":"publisher","DOI":"10.1542\/peds.108.2.473"},{"key":"bibr8-03000605211067694","volume-title":"Guy\u2019s and St Thomas\u2019 Hospital Trust. Chemical Incident Response Service. The chemical incident management handbook. 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