{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T19:29:33Z","timestamp":1792265373021,"version":"4.4.0"},"reference-count":55,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>A meta-analysis to investigate the risk factors for postoperative hypocalcaemia after thyroidectomy in adult patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A systematic search of publications in the electronic databases (PubMed\u00ae, The Cochrane Library, Web of Science, OVID and Embase\u00ae) from inception to June 2020 was conducted. Screening of titles, abstracts and full texts and data extraction were independently performed by two authors. The OR was selected as the pooled estimate.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The analysis included 23 studies. Twelve significant risk factors for postoperative hypocalcaemia were identified: hypoparathyroidism, OR 5.58; total thyroidectomy, OR 3.59; hypomagnesaemia, OR 2.85; preoperative vitamin D deficiency, OR 2.32; female sex, OR 1.49; thyroid malignancy, OR 1.85; thyroiditis, OR 1.48; substernal multinodular goitres, OR 1.70; parathyroidectomy, OR 1.58; central compartment neck dissection, OR 1.17; modified radical neck dissection, OR 1.57; and central neck dissection, OR 1.54.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This meta-analysis provides moderate-to-high quality evidence that the 12 risk factors were predictive of postoperative hypocalcaemia, which should be monitored closely before thyroidectomy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0300060521996911","type":"journal-article","created":{"date-parts":[[2021,3,29]],"date-time":"2021-03-29T08:50:55Z","timestamp":1617007855000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":54,"title":["Risk factors for postoperative hypocalcaemia after thyroidectomy: A systematic review and meta-analysis"],"prefix":"10.1177","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6133-7163","authenticated-orcid":false,"given":"Zhimei","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Nursing, Second Affiliated Hospital of Zhejiang University, Hangzhou, Zhejiang Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiyuan","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Nursing, School of Medicine, Huzhou University, Huzhou, Zhejiang Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinlei","family":"Du","sequence":"additional","affiliation":[{"name":"Department of Nursing, School of Medicine, Huzhou University, Huzhou, Zhejiang Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ya","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Nursing, School of Medicine, Huzhou University, Huzhou, Zhejiang Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rongrong","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Nursing, School of Medicine, Huzhou University, Huzhou, Zhejiang Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caijuan","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Nursing, Second Affiliated Hospital of Zhejiang University, Hangzhou, Zhejiang Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaofang","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Nursing, School of Medicine, Huzhou University, Huzhou First People's Hospital, Huzhou, Zhejiang Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Shu","sequence":"additional","affiliation":[{"name":"Department of Nursing, School of Medicine, Huzhou University, Huzhou, Zhejiang Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,3,29]]},"reference":[{"key":"bibr1-0300060521996911","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2020.05.017"},{"key":"bibr2-0300060521996911","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2019.08.035"},{"key":"bibr3-0300060521996911","doi-asserted-by":"publisher","DOI":"10.1002\/lary.26448"},{"key":"bibr4-0300060521996911","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2016.08.021"},{"key":"bibr5-0300060521996911","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-014-2622-z"},{"key":"bibr6-0300060521996911","doi-asserted-by":"publisher","DOI":"10.1308\/rcsann.2018.0219"},{"key":"bibr7-0300060521996911","first-page":"698","volume":"44","author":"An CM","year":"2009","journal-title":"Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi"},{"key":"bibr8-0300060521996911","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2014.0522"},{"key":"bibr9-0300060521996911","doi-asserted-by":"publisher","DOI":"10.1007\/s13304-017-0452-x"},{"key":"bibr10-0300060521996911","doi-asserted-by":"publisher","DOI":"10.1002\/hed.23937"},{"key":"bibr11-0300060521996911","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2014.0101"},{"key":"bibr12-0300060521996911","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2018.05.737"},{"key":"bibr13-0300060521996911","doi-asserted-by":"publisher","DOI":"10.1007\/s10654-010-9491-z"},{"key":"bibr14-0300060521996911","unstructured":"Wells GA, Shea B, O\u2019Connell D, et\u00a0al.\u00a0The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses, http:\/\/www.ohri.ca\/programs\/clinical_epidemiology\/oxford.asp (2008, accessed January 2019)."},{"key":"bibr15-0300060521996911","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2019.4193"},{"key":"bibr16-0300060521996911","doi-asserted-by":"publisher","DOI":"10.1016\/j.asjsur.2018.12.009"},{"key":"bibr17-0300060521996911","doi-asserted-by":"publisher","DOI":"10.1590\/1516-3180.2018.0336140319"},{"key":"bibr18-0300060521996911","doi-asserted-by":"publisher","DOI":"10.2147\/CMAR.S218179"},{"key":"bibr19-0300060521996911","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2018.05.014"},{"key":"bibr20-0300060521996911","doi-asserted-by":"publisher","DOI":"10.1186\/s12893-017-0258-2"},{"key":"bibr21-0300060521996911","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2017.01.085"},{"key":"bibr22-0300060521996911","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2016.08.019"},{"key":"bibr23-0300060521996911","doi-asserted-by":"publisher","DOI":"10.1177\/0194599816644594"},{"key":"bibr24-0300060521996911","doi-asserted-by":"publisher","DOI":"10.2147\/TCRM.S110464"},{"key":"bibr25-0300060521996911","doi-asserted-by":"publisher","DOI":"10.1007\/s00423-015-1311-1"},{"key":"bibr26-0300060521996911","doi-asserted-by":"publisher","DOI":"10.1177\/0194599814561209"},{"key":"bibr27-0300060521996911","doi-asserted-by":"publisher","DOI":"10.1002\/hed.23613"},{"key":"bibr28-0300060521996911","doi-asserted-by":"publisher","DOI":"10.1016\/j.ciresp.2012.09.006"},{"key":"bibr29-0300060521996911","doi-asserted-by":"publisher","DOI":"10.5402\/2012\/838614"},{"key":"bibr30-0300060521996911","doi-asserted-by":"publisher","DOI":"10.1007\/s12070-009-0083-8"},{"key":"bibr31-0300060521996911","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2008.01.032"},{"key":"bibr32-0300060521996911","doi-asserted-by":"publisher","DOI":"10.2147\/CMAR.S148090"},{"key":"bibr33-0300060521996911","first-page":"w14513","volume":"147","author":"Aqtashi B","year":"2017","journal-title":"Swiss Med Wkly"},{"key":"bibr34-0300060521996911","doi-asserted-by":"publisher","DOI":"10.15605\/jafes.031.01.06"},{"key":"bibr35-0300060521996911","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0207088"},{"key":"bibr36-0300060521996911","doi-asserted-by":"publisher","DOI":"10.4174\/jkss.2012.83.2.75"},{"key":"bibr37-0300060521996911","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-002-6426-1"},{"key":"bibr38-0300060521996911","doi-asserted-by":"publisher","DOI":"10.1186\/s12893-019-0483-y"},{"key":"bibr39-0300060521996911","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-008-9894-0"},{"key":"bibr40-0300060521996911","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.890721"},{"key":"bibr41-0300060521996911","first-page":"182","volume":"74","author":"Nam KH","year":"2008","journal-title":"J Korean Surg Soc"},{"key":"bibr42-0300060521996911","doi-asserted-by":"publisher","DOI":"10.1177\/1081558905053001568"},{"key":"bibr43-0300060521996911","first-page":"289","volume":"17","author":"Chattopadhyay N","year":"1996","journal-title":"Endocr Rev"},{"key":"bibr44-0300060521996911","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gft400"},{"key":"bibr45-0300060521996911","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2020.543099"},{"key":"bibr46-0300060521996911","first-page":"675","volume":"22","author":"Sebastian M","year":"2013","journal-title":"Adv Clin Exp Med"},{"key":"bibr47-0300060521996911","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2003.11.017"},{"key":"bibr48-0300060521996911","doi-asserted-by":"publisher","DOI":"10.1172\/JCI109312"},{"key":"bibr49-0300060521996911","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(91)90201-Y"},{"key":"bibr50-0300060521996911","doi-asserted-by":"publisher","DOI":"10.1002\/hed.20728"},{"key":"bibr51-0300060521996911","first-page":"29","volume":"11","author":"Rajinikanth J","year":"2009","journal-title":"Medscape J Med"},{"key":"bibr52-0300060521996911","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000250451.59685.67"},{"key":"bibr53-0300060521996911","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2482-13-S2-S11"},{"key":"bibr54-0300060521996911","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2017.01.011"},{"key":"bibr55-0300060521996911","first-page":"e5920","volume":"11","author":"Karadeniz E","year":"2019","journal-title":"Cureus"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300060521996911","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0300060521996911","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300060521996911","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:48:31Z","timestamp":1777459711000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0300060521996911"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3]]},"references-count":55,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["10.1177\/0300060521996911"],"URL":"https:\/\/doi.org\/10.1177\/0300060521996911","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3]]},"article-number":"0300060521996911"}}