{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T13:09:44Z","timestamp":1777727384212,"version":"3.51.4"},"reference-count":21,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["No. 2020M3A9E8024907"],"award-info":[{"award-number":["No. 2020M3A9E8024907"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Children with acute lymphoblastic leukemia (ALL) may be at increased risk of psychiatric disorders. This study analyzed the incidence of psychiatric disorders in children with ALL in South Korea.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Using nationwide claims data for January 2009 to March 2016, we identified three major psychiatric disorders (depression, anxiety and stress\/adjustment disorder) among children diagnosed with ALL. We analyzed the incidence of psychiatric disorders before and after ALL diagnosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Overall, 2160 children diagnosed with ALL were identified. Seventy-five children (3.5%) were diagnosed with at least one major psychiatric disorder from 1 year before ALL diagnosis to the last follow-up point (range: 42.5\u2013111.5 months). Of these, 70 (93.3%) patients were identified after ALL diagnosis, with the incidence peaking 1 year after ALL diagnosis. Depression, anxiety and stress\/adjustment disorders were diagnosed in 30 (1.4%), 15 (0.7%) and 30 (1.4%) patients, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Among pediatric patients with ALL, most psychiatric disorders were identified after the diagnosis of leukemia, and psychiatric disorder incidence differed according to patient age and time since ALL diagnosis. Timely screening for and proper management of mental disorders are needed during all stages of ALL treatment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/03000605221075223","type":"journal-article","created":{"date-parts":[[2022,1,28]],"date-time":"2022-01-28T01:06:42Z","timestamp":1643332002000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Psychiatric disorders among children with acute lymphoblastic leukemia in South Korea: a nationwide population-based longitudinal study"],"prefix":"10.1177","volume":"50","author":[{"given":"Jaesung","family":"Heo","sequence":"first","affiliation":[{"name":"Department of Radiation Oncology, Ajou University School of Medicine, Suwon, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun Eun","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Korea University College of Medicine, Seoul, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9066-780X","authenticated-orcid":false,"given":"O Kyu","family":"Noh","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Ajou University School of Medicine, Suwon, Republic of Korea"},{"name":"Department of Biomedical Informatics, Ajou University School of Medicine, Suwon, Republic of Korea"},{"name":"Office of Biostatistics, Ajou Research Institute for Innovative Medicine, Suwon, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yunmi","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Ajou University School of Medicine, Suwon, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,1,27]]},"reference":[{"key":"bibr1-03000605221075223","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.29708"},{"key":"bibr2-03000605221075223","doi-asserted-by":"publisher","DOI":"10.3345\/kjp.2017.60.5.129"},{"key":"bibr3-03000605221075223","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2017.32.4.642"},{"key":"bibr4-03000605221075223","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.29946"},{"key":"bibr5-03000605221075223","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.24079"},{"key":"bibr6-03000605221075223","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.27356"},{"key":"bibr7-03000605221075223","doi-asserted-by":"publisher","DOI":"10.2147\/COAYA.S49174"},{"key":"bibr8-03000605221075223","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.24096"},{"key":"bibr9-03000605221075223","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2017.32.5.718"},{"key":"bibr10-03000605221075223","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-147-8-200710160-00010"},{"key":"bibr11-03000605221075223","unstructured":"Kliegman RM, Geme JS.\n                      Nelson textbook of pediatrics. Mood disorders\n                      . Elsevier Health Sciences, 2019."},{"key":"bibr12-03000605221075223","unstructured":"Hong K, Ahn D, Lee Y, et\u00a0al.\n                      Textbook of child psychiatry\n                      . 1st ed. Hakjisa, 2014, pp.233\u2013252."},{"key":"bibr13-03000605221075223","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.29876"},{"key":"bibr14-03000605221075223","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.28578"},{"key":"bibr15-03000605221075223","doi-asserted-by":"publisher","DOI":"10.1002\/mpo.2950200104"},{"key":"bibr16-03000605221075223","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.23060"},{"key":"bibr17-03000605221075223","doi-asserted-by":"publisher","DOI":"10.1002\/pon.4628"},{"key":"bibr18-03000605221075223","first-page":"e125","volume":"16","author":"Heo J","year":"2019","journal-title":"Asia Pac J Clin Oncol"},{"key":"bibr19-03000605221075223","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.25425"},{"key":"bibr20-03000605221075223","first-page":"229","volume":"28","author":"Merenda PF.","year":"1996","journal-title":"Measurement and Evaluation in Counseling and Development"},{"key":"bibr21-03000605221075223","doi-asserted-by":"publisher","DOI":"10.4306\/jknpa.2016.55.4.299"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03000605221075223","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/03000605221075223","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03000605221075223","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:49:17Z","timestamp":1777459757000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/03000605221075223"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":21,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1]]}},"alternative-id":["10.1177\/03000605221075223"],"URL":"https:\/\/doi.org\/10.1177\/03000605221075223","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1]]},"article-number":"03000605221075223"}}