{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:00:59Z","timestamp":1787166059246,"version":"build-2736575974"},"reference-count":37,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Anhui Famous Traditional Chinese Medicine Liu Jian Studio Construction Project","award":["Traditional Chinese Medicine Development Secret [2"],"award-info":[{"award-number":["Traditional Chinese Medicine Development Secret [2"]}]},{"name":"Key Research and Development Plan Project of Anhui Province","award":["201904a07020004"],"award-info":[{"award-number":["201904a07020004"]}]},{"name":"The Key Laboratory of Xin'an Ministry of Medical Education","award":["No.2020xayx10"],"award-info":[{"award-number":["No.2020xayx10"]}]},{"name":"National Nature Fund Program","award":["82074373"],"award-info":[{"award-number":["82074373"]}]},{"name":"Anhui Key Research and Development Program Foreign Science and Technology Cooperation Project","award":["201904b11020011"],"award-info":[{"award-number":["201904b11020011"]}]},{"name":"The University Synergy Innovation Program of Anhui Province","award":["GXXT-2020-025"],"award-info":[{"award-number":["GXXT-2020-025"]}]},{"name":"the Ministry of Science and Technology National Key Research and Development Program Chinese Medicine Modernization Research Key Project","award":["2018YFC1705204"],"award-info":[{"award-number":["2018YFC1705204"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study examined the relationship of the Sharp score with demographic factors and clinical immune-inflammatory markers in patients with anemia in rheumatoid arthritis (RA).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The clinical data of 1057 patients with RA and anemia and 1006 patients with RA without anemia were retrospectively analyzed. Spearman\u2019s correlation coefficient analysis, association rule analysis, and logistic regression were used to study the relationships between the Sharp score and influencing factors in patients with RA and anemia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The incidence of anemia was 51.24% (1057\/2063), and mild anemia accounted for 81.93% (866\/1057) of cases. Spearman\u2019s correlation coefficient and association rule analyses revealed that the Sharp score of patients with RA and anemia was correlated with immune-inflammatory response and anemia. Logistic regression analysis illustrated that advanced age (&gt;60 years), female, low serum iron levels, C-reactive protein positivity, and immunoglobulin A positivity were risk factors for a high Sharp score (&gt;28.25) in patients with RA and anemia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The Sharp score is closely related to clinical disease activity and anemia, and it should be considered in the treatment strategy of patients with RA and anemia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/03000605221088560","type":"journal-article","created":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T01:55:23Z","timestamp":1648518923000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Factors influencing the Sharp score of 1057 patients with rheumatoid arthritis and anemia: a retrospective study"],"prefix":"10.1177","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8361-5865","authenticated-orcid":false,"given":"Yanqiu","family":"Sun","sequence":"first","affiliation":[{"name":"Anhui University of Traditional Chinese Medicine, Hefei 230031, Anhui Province, China"},{"name":"Institute of Rheumatology, Anhui Academy of Chinese Medicine, Hefei 230012, Anhui Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Immunology, First Affiliated Hospital of Anhui University of Traditional Chinese Medicine, Hefei 230038, Anhui Province, China"},{"name":"Institute of Rheumatology, Anhui Academy of Chinese Medicine, Hefei 230012, Anhui Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"Xin","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Immunology, First 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