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Here, we report the case of a patient in their late 50s with severe pancytopenia post-autologous stem cell transplantation reinfusion suffering from splenic rupture after treatment with lenograstim. We also reviewed the literature describing cases of splenic rupture during G-CSF administration.<\/jats:p>","DOI":"10.1177\/03000605221095504","type":"journal-article","created":{"date-parts":[[2022,5,31]],"date-time":"2022-05-31T07:17:26Z","timestamp":1653981446000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Splenic rupture following lenograstim in post-autologous stem cell transplantation treated with emergency open splenectomy: a case report and literature review"],"prefix":"10.1177","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0868-5676","authenticated-orcid":false,"given":"Uros","family":"Markovic","sequence":"first","affiliation":[{"name":"Oncohematology and BMT Unit, Mediterranean Institute of Oncology, Viagrande, Italy"},{"name":"Department of Biomedical, Dental, Morphological and Functional Imaging Sciences, University of Messina, Messina, 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