{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T23:33:26Z","timestamp":1791502406820,"version":"4.3.4"},"reference-count":49,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Asociaci\u00f3n Colombiana de Facultades de Medicina","award":["887-2020"],"award-info":[{"award-number":["887-2020"]}]},{"DOI":"10.13039\/501100007626","name":"Universidad de Caldas","doi-asserted-by":"publisher","award":["0340420"],"award-info":[{"award-number":["0340420"]}],"id":[{"id":"10.13039\/501100007626","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100019346","name":"Instituto Nacional de Cancerolog\u00eda","doi-asserted-by":"crossref","award":["0096-2021"],"award-info":[{"award-number":["0096-2021"]}],"id":[{"id":"10.13039\/100019346","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Ministerio de Ciencia, Tecnolog\u00eda e Innovaci\u00f3n de Colombia","award":["887-2020"],"award-info":[{"award-number":["887-2020"]}]},{"name":"Instituto Cient\u00edfico Pfizer Colombia","award":["887-2020"],"award-info":[{"award-number":["887-2020"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>We estimated the cutaneous melanoma (CM) incidence, mortality, and survival in Manizales, Colombia to establish predictors for survival.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This analytical cohort study used CM incident cases during 2006 to 2015 in the Manizales Cancer Registry (n\u2009=\u2009132). Incidence and mortality rates were standardized using the direct method. Patients were followed up until 30 November 2020. Cause-specific survival was calculated using the Kaplan\u2013Meier method for variables of interest, with the log-rank test for differences. Cox multivariate regression models were fitted.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Incidence (per 100,000) increased from 1.6 to 3.0 in men and 2.6 to 2.8 in women during 2006\u20132010 to 2011\u20132015, respectively. Mortality was low and stable. Five-year survival was 68.7%, with significant differences according to age (hazard ratio [HR] &gt;70 vs. \u226470 years: 3.37); histological subtype (HR for melanoma not otherwise specified and HR for nodular melanoma vs lentigo malignant melanoma and superficial spreading melanoma: 17.39 and 10.16, respectively); and clinical stage (HR stages III\u2013IV vs. stages I\u2013II: 5.94).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>CM is characterized by increasing incidence and unfavorable prognosis, particularly in patients aged &gt;70 years, with melanoma not otherwise specified and nodular melanoma, and advanced stages. Promoting photoprotection and early detection and management of suspicious skin lesions is crucial.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/03000605221106706","type":"journal-article","created":{"date-parts":[[2022,6,20]],"date-time":"2022-06-20T01:18:13Z","timestamp":1655687893000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":14,"title":["Cutaneous melanoma incidence, mortality, and survival in Manizales, Colombia: a population-based study"],"prefix":"10.1177","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2192-458X","authenticated-orcid":false,"given":"Juan David","family":"Rodr\u00edguez-Betancourt","sequence":"first","affiliation":[{"name":"Young Researchers Program, Ministerio de Ciencia, Tecnolog\u00eda e Innovaci\u00f3n, Bogot\u00e1, Colombia"},{"name":"Population-based Manizales Cancer Registry, Instituto de Investigaciones en Salud, Universidad de Caldas, Manizales, Colombia"},{"name":"Departamento de Salud P\u00fablica, Universidad de Caldas, Manizales, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5093-3384","authenticated-orcid":false,"given":"Nelson","family":"Arias-Ortiz","sequence":"additional","affiliation":[{"name":"Population-based Manizales Cancer Registry, Instituto de Investigaciones en Salud, Universidad de Caldas, Manizales, Colombia"},{"name":"Departamento de Salud P\u00fablica, Universidad de Caldas, Manizales, Colombia"},{"name":"Grupo de Investigaci\u00f3n Promoci\u00f3n de la Salud y Prevenci\u00f3n de la Enfermedad, Universidad de Caldas, Manizales, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,6,19]]},"reference":[{"key":"bibr1-03000605221106706","first-page":"1","volume":"0","author":"Sung H","year":"2021","journal-title":"CA Cancer J Clin"},{"key":"bibr2-03000605221106706","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2018.2706"},{"key":"bibr3-03000605221106706","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)33326-3"},{"key":"bibr4-03000605221106706","doi-asserted-by":"publisher","DOI":"10.1016\/j.canep.2016.02.005"},{"key":"bibr5-03000605221106706","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.13839"},{"key":"bibr6-03000605221106706","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-016-5394-x"},{"key":"bibr7-03000605221106706","doi-asserted-by":"publisher","DOI":"10.1186\/s13104-015-0972-8"},{"key":"bibr8-03000605221106706","doi-asserted-by":"publisher","DOI":"10.1007\/s12094-017-1685-3"},{"key":"bibr9-03000605221106706","doi-asserted-by":"publisher","DOI":"10.1097\/CMR.0000000000000476"},{"key":"bibr10-03000605221106706","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2011.10772.x"},{"key":"bibr11-03000605221106706","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2013.5853"},{"key":"bibr12-03000605221106706","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2009.05.009"},{"key":"bibr13-03000605221106706","doi-asserted-by":"publisher","DOI":"10.29176\/2590843X.317"},{"key":"bibr14-03000605221106706","doi-asserted-by":"publisher","DOI":"10.1590\/S1020-49892011001100005"},{"key":"bibr15-03000605221106706","doi-asserted-by":"publisher","DOI":"10.1016\/S0123-9015(13)70160-4"},{"key":"bibr16-03000605221106706","unstructured":"DANE. 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