{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T13:17:29Z","timestamp":1777727849649,"version":"3.51.4"},"reference-count":28,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"crossref","award":["NRF-2019R1G1A1100523"],"award-info":[{"award-number":["NRF-2019R1G1A1100523"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Interlaminar cervical epidural steroid injections (ICESIs) are commonly used to treat axial neck pain and cervical radicular pain. However, local anesthetics can spread to and block the phrenic nerve and upper segments of the thoracic spinal cord where the sympathetic innervation of the lungs emerges. Therefore, changes in lung function may occur following ICESIs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The primary outcome measure was the pulmonary function test (PFT) result 30 minutes before and after ICESI with ropivacaine (0.1875% or 0.25%). The secondary outcome measure was the comparison of the pain scores and functional disability between the two concentrations of ropivacaine 4 weeks after the ICESIs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Fifty patients were randomly assigned to either the R1 (0.1875% ropivacaine) or R2 (0.25% ropivacaine) group. No significant difference was observed between the pre-ICESI and 30-minute post-ICESI PFT results within each group, and no difference was observed between the two groups. After 4 weeks of treatment, both groups showed a significant decrease in pain scores and functional disability; however, no significant differences were observed between the two groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study showed no significant change in lung function after ICESIs in either group and no local anesthetic concentration-based difference in the clinical efficacy of the ICESIs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/03000605221108101","type":"journal-article","created":{"date-parts":[[2022,6,29]],"date-time":"2022-06-29T05:05:46Z","timestamp":1656479146000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of lung function and clinical features of interlaminar cervical epidural steroid injections: a randomized controlled trial"],"prefix":"10.1177","volume":"50","author":[{"given":"Ji Seon","family":"Chae","sequence":"first","affiliation":[{"name":"Department of Anesthesiology and Pain Medicine, College of Medicine, Ewha Womans University, Seoul, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2046-8690","authenticated-orcid":false,"given":"Won-joong","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Pain Medicine, College of Medicine, Ewha Womans University, Seoul, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gi Year","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Pain Medicine, College of Medicine, Ewha Womans University, Ewha Womans University Mokdong Hospital, Seoul, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong Ju","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Pain Medicine, College of Medicine, Ewha Womans University, Ewha Womans University Mokdong Hospital, Seoul, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,6,29]]},"reference":[{"key":"bibr1-03000605221108101","doi-asserted-by":"publisher","DOI":"10.3344\/kjp.2016.29.2.96"},{"key":"bibr2-03000605221108101","first-page":"445","volume":"7","author":"Derby R","year":"2004","journal-title":"Pain Physician"},{"key":"bibr3-03000605221108101","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-199504000-00021"},{"key":"bibr4-03000605221108101","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0b013e318145a360"},{"key":"bibr5-03000605221108101","doi-asserted-by":"publisher","DOI":"10.1007\/BF03015258"},{"key":"bibr6-03000605221108101","first-page":"395","volume":"21","author":"Hogan QH.","year":"1996","journal-title":"Reg Anesth"},{"key":"bibr7-03000605221108101","first-page":"155","volume":"16","author":"Lee SE","year":"2013","journal-title":"Pain Physician"},{"key":"bibr8-03000605221108101","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1986.sp016218"},{"key":"bibr9-03000605221108101","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4522(92)90239-X"},{"key":"bibr10-03000605221108101","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3959(00)00229-3"},{"key":"bibr11-03000605221108101","doi-asserted-by":"publisher","DOI":"10.1093\/pm\/pnw057"},{"key":"bibr12-03000605221108101","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/82.2.217"},{"key":"bibr13-03000605221108101","doi-asserted-by":"publisher","DOI":"10.1016\/j.jse.2012.06.011"},{"key":"bibr14-03000605221108101","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000001945"},{"key":"bibr15-03000605221108101","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aev342"},{"key":"bibr16-03000605221108101","doi-asserted-by":"publisher","DOI":"10.36076\/ppj.2013\/16\/353"},{"key":"bibr17-03000605221108101","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000009444"},{"key":"bibr18-03000605221108101","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.c332"},{"key":"bibr19-03000605221108101","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0b013e3181df78e9"},{"key":"bibr20-03000605221108101","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2005.01.350"},{"key":"bibr21-03000605221108101","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1213\/00000539-199805000-00025","volume":"86","author":"Capdevila X","year":"1998","journal-title":"Anesth Analg"},{"key":"bibr22-03000605221108101","unstructured":"Furman MB, Lee TS, Berkwits L. 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