{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T05:16:04Z","timestamp":1790745364175,"version":"4.1.0"},"reference-count":40,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:p>Although anaphylaxis during anaesthesia is a rare event, neuromuscular blocking drugs are responsible for 62% of anaesthesia-related anaphylaxis. However, sugammadex, a modified gamma-cyclodextrin, can encapsulate rocuronium molecules and cause the rapid reversal of the neuromuscular blockade. A 68-year-old man who presented for a radical prostatectomy was induced with IV fentanyl\/propofol\/rocuronium. He had not received rocuronium previously but had received cisatracurium. Shortly after anaesthesia, the patient\u2019s heart rate abruptly increased, and systolic blood pressure (SBP) dropped to 40\u2009mm\u2009Hg. Despite cardiopulmonary resuscitation and intensive management, his haemodynamic stability did not improve until he received IV sugammadex, 200\u2009mg. Intradermal skin tests showed he was positive for cisatracurium, rocuronium and succinylcholine. The patient was suspected to have cross-reactivity of rocuronium with cisatracurium. This case highlights the potential benefit of sugammadex as an adjunct to conventional measures during rocuronium-induced anaphylaxis.<\/jats:p>","DOI":"10.1177\/03000605221113913","type":"journal-article","created":{"date-parts":[[2022,7,23]],"date-time":"2022-07-23T01:26:48Z","timestamp":1658539608000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Successful management of rocuronium-induced anaphylaxis with sugammadex: A case report"],"prefix":"10.1177","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9905-963X","authenticated-orcid":false,"given":"Sheng-Kai","family":"Hung","sequence":"first","affiliation":[{"name":"Department of Anaesthesiology, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8960-0461","authenticated-orcid":false,"given":"Chia-Chi","family":"Yeh","sequence":"additional","affiliation":[{"name":"Department of Family Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei-Chi","family":"Ting","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, New Taipei Municipal TuCheng Hospital (Built and Operated by Chang Gung Medical Foundation), New Taipei City, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cay-Huyen","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3639-5318","authenticated-orcid":false,"given":"Ming-Chang","family":"Kao","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, New Taipei Municipal TuCheng Hospital (Built and Operated by Chang Gung Medical Foundation), New Taipei City, Taiwan"},{"name":"Department of Anaesthesiology, New Taipei Municipal TuCheng Hospital, No. 6, Sec. 2, Jincheng Rd., Tucheng Dist., New Taipei City, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,7,22]]},"reference":[{"key":"bibr1-03000605221113913","doi-asserted-by":"publisher","DOI":"10.1016\/S0750-7658(05)81016-0"},{"key":"bibr2-03000605221113913","doi-asserted-by":"publisher","DOI":"10.1016\/S0750-7658(00)88460-9"},{"key":"bibr3-03000605221113913","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0000000000000512"},{"key":"bibr4-03000605221113913","doi-asserted-by":"publisher","DOI":"10.1016\/j.bja.2019.01.027"},{"key":"bibr5-03000605221113913","doi-asserted-by":"publisher","DOI":"10.1016\/S1081-1206(10)60883-6"},{"key":"bibr6-03000605221113913","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.161.1.15"},{"key":"bibr7-03000605221113913","doi-asserted-by":"publisher","DOI":"10.3390\/medicina57020088"},{"key":"bibr8-03000605221113913","doi-asserted-by":"publisher","DOI":"10.4103\/joacp.JOACP_383_19"},{"key":"bibr9-03000605221113913","doi-asserted-by":"publisher","DOI":"10.1213\/01.ane.0000244594.63318.fc"},{"key":"bibr10-03000605221113913","doi-asserted-by":"publisher","DOI":"10.1111\/head.12246"},{"key":"bibr11-03000605221113913","first-page":"138","volume":"15","author":"Lagopoulos V","year":"2011","journal-title":"Hippokratia"},{"key":"bibr12-03000605221113913","doi-asserted-by":"publisher","DOI":"10.1159\/isbn.978-3-318-01454-9"},{"key":"bibr13-03000605221113913","unstructured":"Doan T, Melvold R, Viselli S, et\u00a0al. 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