{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T13:11:07Z","timestamp":1777727467383,"version":"3.51.4"},"reference-count":8,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:p>The potential utility of nifekalant, a new Class III antiarrhythmic drug, to offer long-term protection against ventricular arrhythmia has been investigated in this case report. A 44-year-old male patient with dilated cardiomyopathy complicated with heart failure and persistent ventricular tachycardia was treated with nifekalant. The patient was treated with nifekalant for 31 days, which effectively terminated ventricular tachycardia and maintained sinus rhythm, with no clinical adverse reactions. After heart transplantation, postoperative follow-up showed good cardiac function and no arrhythmia. On the basis of nifekalant\u2019s working mechanism, there is a good chance that it can cure ventricular arrhythmia on a long-term basis.<\/jats:p>","DOI":"10.1177\/03000605221133704","type":"journal-article","created":{"date-parts":[[2022,10,27]],"date-time":"2022-10-27T03:44:03Z","timestamp":1666842243000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Long-term nifekalant use in a patient with dilated cardiomyopathy and recurrent ventricular tachycardia"],"prefix":"10.1177","volume":"50","author":[{"given":"Hongyan","family":"Xiao","sequence":"first","affiliation":[{"name":"Department of Cardiac Surgery, Wuhan Asia Heart Hospital Affiliated with the Wuhan University of Science and Technology, Wuhan, Hubei, P.R. China"},{"name":"Wuhan Clinical Research Center for Cardiomyopathy, Wuhan, Hubei, P.R. 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