{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T12:59:54Z","timestamp":1777726794561,"version":"3.51.4"},"reference-count":23,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Medical Key Support Disciplines Foundation of Suzhou","award":["No. SZFCXK202134"],"award-info":[{"award-number":["No. SZFCXK202134"]}]},{"DOI":"10.13039\/501100018556","name":"Science and Technology Program of Suzhou","doi-asserted-by":"crossref","award":["No. SYS2020069"],"award-info":[{"award-number":["No. SYS2020069"]}],"id":[{"id":"10.13039\/501100018556","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>We aimed to develop a nomogram to predict the risk of severe influenza in previously healthy children.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this retrospective cohort study, we reviewed the clinical data of 1135 previously healthy children infected with influenza who were hospitalized in the Children's Hospital of Soochow University between 1 January 2017 and 30 June 2021. Children were randomly assigned in a 7:3 ratio to a training or validation cohort. In the training cohort, univariate and multivariate logistic regression analyses were used to identify risk factors, and a nomogram was established. The validation cohort was used to evaluate the predictive ability of the model.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Result<\/jats:title>\n                    <jats:p>Wheezing rales, neutrophils, procalcitonin\u2009&gt;\u20090.25\u2009ng\/mL, Mycoplasma pneumoniae infection, fever, and albumin were selected as predictors. The areas under the curve were 0.725 (95% CI: 0.686\u20130.765) and 0.721 (95% CI: 0.659\u20130.784) for the training and validation cohorts, respectively. The calibration curve showed that the nomogram was well calibrated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The nomogram may predict the risk of severe influenza in previously healthy children.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/03000605231153768","type":"journal-article","created":{"date-parts":[[2023,2,20]],"date-time":"2023-02-20T02:50:10Z","timestamp":1676861410000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Development of a nomogram for severe influenza in previously healthy children: a retrospective cohort study"],"prefix":"10.1177","volume":"51","author":[{"given":"Wenyun","family":"Huang","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine, Children's Hospital of Soochow University, Suzhou, China"},{"name":"Department of Pediatrics, Suzhou Wujiang District Children\u2019s Hospital (Children's Hospital of Soochow University Wujiang Branch), Suzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wensi","family":"Niu","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Suzhou Wujiang District Children\u2019s Hospital (Children's Hospital of Soochow University Wujiang Branch), Suzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongmei","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Children's Hospital of Soochow University, Suzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wujun","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Suzhou Wujiang District Children\u2019s Hospital (Children's Hospital of Soochow University Wujiang Branch), Suzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanbing","family":"Fu","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Children's Hospital of Soochow University, Suzhou, China"},{"name":"Department of Pediatrics, Suzhou Wujiang District Children\u2019s Hospital (Children's Hospital of Soochow University Wujiang Branch), Suzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiuxiu","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Children's Hospital of Soochow University, Suzhou, China"},{"name":"Department of Pediatrics, Suzhou Wujiang District Children\u2019s Hospital (Children's Hospital of Soochow University Wujiang Branch), Suzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minglei","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Children's Hospital of Soochow University, Suzhou, China"},{"name":"Department of Pediatrics, Suzhou Wujiang District Children\u2019s Hospital (Children's Hospital of Soochow University Wujiang Branch), Suzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9610-807X","authenticated-orcid":false,"given":"Jun","family":"Hua","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Children's Hospital of Soochow University, Suzhou, China"},{"name":"Department of Pediatrics, Suzhou Wujiang District Children\u2019s Hospital (Children's Hospital of Soochow University Wujiang Branch), Suzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chunxia","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Suzhou Wujiang District Children\u2019s Hospital (Children's Hospital of Soochow University Wujiang Branch), Suzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,2,19]]},"reference":[{"key":"bibr1-03000605231153768","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(19)30545-5"},{"key":"bibr2-03000605231153768","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-82161-z"},{"key":"bibr3-03000605231153768","first-page":"1722","volume":"42","author":"National Immunization Advisory Committee Technical Working Group. 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