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This current case report describes the sixth case of ASPS in a 15-year-old male that presented with recurrent headaches. Head computed tomography showed space-occupying lesions in the left parietal lobe. Positron emission tomography\u2013computed tomography confirmed the space-occupying lesions in the left parietal lobe and showed multiple nodules and masses in the two lungs and pleura, which were considered to be low-grade malignant mesenchymal tumours. The case report presents the clinical characteristics, diagnosis and treatment process. Programmed cell death protein 1 monoclonal antibody (sintilimab) combined with a tyrosine kinase inhibitor (anlotinib hydrochloride) achieved a good therapeutic effect, indicating that this combination therapy is worth exploring further. Large-scale prospective studies are needed to explore and develop standardized treatments for ASPS.<\/jats:p>","DOI":"10.1177\/03000605231174973","type":"journal-article","created":{"date-parts":[[2023,6,7]],"date-time":"2023-06-07T03:27:36Z","timestamp":1686108456000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Treatment of a case of primary alveolar soft part sarcoma of the lung: Case report and literature review"],"prefix":"10.1177","volume":"51","author":[{"given":"Feiyang","family":"Li","sequence":"first","affiliation":[{"name":"Ward 2, Department of Medical Oncology, Lixin County People's Hospital, Bozhou, Anhui Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4463-995X","authenticated-orcid":false,"given":"Haowei","family":"Lu","sequence":"additional","affiliation":[{"name":"Ward 2, Department of Medical Oncology, Lixin County People's Hospital, Bozhou, Anhui Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong","family":"Zhao","sequence":"additional","affiliation":[{"name":"Ward 2, Department of Medical Oncology, Lixin County People's Hospital, Bozhou, Anhui Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiyuan","family":"Shen","sequence":"additional","affiliation":[{"name":"Ward 2, Department of Medical Oncology, Lixin County People's Hospital, Bozhou, Anhui Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,6,7]]},"reference":[{"key":"bibr1-03000605231174973","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21708"},{"key":"bibr2-03000605231174973","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1002\/jso.25847","volume":"121","author":"Spencer RMSSB","year":"2020","journal-title":"J Surg Oncol"},{"key":"bibr3-03000605231174973","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/4351308"},{"key":"bibr4-03000605231174973","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21605"},{"key":"bibr5-03000605231174973","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2018.04.117"},{"key":"bibr6-03000605231174973","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(195201)5:1<100::AID-CNCR2820050112>3.0.CO;2-K"},{"key":"bibr7-03000605231174973","doi-asserted-by":"publisher","DOI":"10.4055\/cios.2014.6.1.80"},{"key":"bibr8-03000605231174973","doi-asserted-by":"publisher","DOI":"10.21873\/anticanres.14122"},{"key":"bibr9-03000605231174973","first-page":"771","volume":"41","author":"Tsutsumi Y","year":"1991","journal-title":"Acta Pathol Jpn"},{"key":"bibr10-03000605231174973","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2007.22.2.369"},{"key":"bibr11-03000605231174973","doi-asserted-by":"publisher","DOI":"10.1186\/s13000-015-0399-5"},{"key":"bibr12-03000605231174973","doi-asserted-by":"publisher","DOI":"10.1007\/s10637-021-01105-6"},{"key":"bibr13-03000605231174973","doi-asserted-by":"publisher","DOI":"10.1177\/10668969221096869"},{"key":"bibr14-03000605231174973","unstructured":"US Department of Health and Human Services. 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