{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T15:17:14Z","timestamp":1787584634450,"version":"build-2736575974"},"reference-count":15,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:p>Q fever is an important zoonotic disease caused by the pathogen Coxiella burnetii, which is inhaled into the body through the respiratory tract leading to acute symptoms. Severe acute Q fever may result in complications, such as pneumonia, hepatitis, or myocarditis, and some patients may develop chronic Q fever after incomplete treatment. Local persistent C. burnetii infection may lead to chronic Q fever that often requires surgery and anti-infection treatment for several years, seriously endangering patient health and increasing the economic burden for families. The clinicians\u2019 lack of awareness of the disease may be one reason leading to a delay in treatment. Here, a case of Q fever in a 53-year-old male patient, which was diagnosed by next generation sequencing and exhibited a distinct computed tomographic feature, is reported, with the aim of improving clinical knowledge of this disease. Following diagnosis, the patient was treated with 0.1\u2009g doxycycline, orally, twice daily, and 0.5\u2009g chloramphenicol, orally, three times daily, leading to improvement of symptoms and discharge from hospital.<\/jats:p>","DOI":"10.1177\/03000605231183553","type":"journal-article","created":{"date-parts":[[2023,6,29]],"date-time":"2023-06-29T07:08:26Z","timestamp":1688022506000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Q fever represented as multiple pulmonary nodules: a case report"],"prefix":"10.1177","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6194-4767","authenticated-orcid":false,"given":"Yu","family":"Zhai","sequence":"first","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine, People\u2019s Hospital of Rongchang District, Chongqing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,6,29]]},"reference":[{"key":"bibr1-03000605231183553","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms10112168"},{"key":"bibr2-03000605231183553","doi-asserted-by":"publisher","DOI":"10.1111\/os.13600"},{"key":"bibr3-03000605231183553","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.03.00099703"},{"key":"bibr4-03000605231183553","first-page":"1","volume":"62","author":"Anderson A","year":"2013","journal-title":"MMWR Recomm Rep"},{"key":"bibr5-03000605231183553","doi-asserted-by":"publisher","DOI":"10.1016\/S0009-9260(05)80857-8"},{"key":"bibr6-03000605231183553","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.210.2.r99fe20339"},{"key":"bibr7-03000605231183553","doi-asserted-by":"publisher","DOI":"10.1055\/s-0040-1710594"},{"key":"bibr8-03000605231183553","doi-asserted-by":"publisher","DOI":"10.1111\/head.12246"},{"key":"bibr9-03000605231183553","first-page":"791","volume":"111","author":"Van Roeden SE","year":"2018","journal-title":"QJM"},{"key":"bibr10-03000605231183553","volume-title":"Johns Hopkins ABX guide 2012: diagnosis and treatment of infectious diseases","author":"Bartlett JG","year":"2011","edition":"3"},{"key":"bibr11-03000605231183553","volume-title":"The Sanford guide to antimicrobial therapy 2015","author":"Gilbert DN","year":"2015","edition":"45"},{"key":"bibr12-03000605231183553","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.37.9.1733"},{"key":"bibr13-03000605231183553","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cix886"},{"key":"bibr14-03000605231183553","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.215.3.r00jn21880"},{"key":"bibr15-03000605231183553","doi-asserted-by":"publisher","DOI":"10.1259\/bjr.20180292"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03000605231183553","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/03000605231183553","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03000605231183553","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:48:20Z","timestamp":1777459700000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/03000605231183553"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6]]},"references-count":15,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,6]]}},"alternative-id":["10.1177\/03000605231183553"],"URL":"https:\/\/doi.org\/10.1177\/03000605231183553","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,6]]},"article-number":"03000605231183553"}}