{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T13:22:16Z","timestamp":1777728136633,"version":"3.51.4"},"reference-count":18,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Long-term use of antipsychotics or other dopamine antagonists can result in the extrapyramidal side effect of tardive dyskinesia (TD). Case presentation: An 18-year-old female patient experienced abnormal speech and behavior and because of an equivocal diagnosis, she was given daily doses of 300\u2009mg of quetiapine and 60\u2009mg of ziprasidone. She had used these medications for 2 years before the appearance of involuntary abnormal movements. These movements, which were classified as TD, steadily worsened and markedly interfered with her daily life. Following a trial-and-error course of therapy with vitamin E, vitamin B6, amantadine, valproic acid sodium, lorazepam, and diazepam, the drugs were gradually reduced and stopped, yet the aberrant movements persisted. Finally, the patient was given olanzapine, clonazepam, baclofen, and gabapentin. The Abnormal Involuntary Movement Scale was used to assess changes in the patient's condition. Her TD was efficiently managed through co-administration of olanzapine, clonazepam, baclofen, and gabapentin.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The possibility of TD inducing by antipsychotic use is a clinical concern, even though atypical antipsychotics decrease the incidence of extrapyramidal side effects, and it cannot be entirely excluded. This report provides useful insights into the management of TD and will help clinicians manage similar cases.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/03000605231195154","type":"journal-article","created":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T12:19:57Z","timestamp":1696853997000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Treatment of severe tardive dyskinesia with concurrent administration of olanzapine, clonazepam, baclofen, and gabapentin: a case report"],"prefix":"10.1177","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-2046-8372","authenticated-orcid":false,"given":"Xiaoling","family":"Guo","sequence":"first","affiliation":[{"name":"Department of Mental Health, Tongde Hospital of Zhejiang Province, Mental Health Center of Zhejiang Province, Hangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiong","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Mental Health, Tongde Hospital of Zhejiang Province, Mental Health Center of Zhejiang Province, Hangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weixin","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Mental Health, Tongde Hospital of Zhejiang Province, Mental Health Center of Zhejiang Province, Hangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Mental Health, Tongde Hospital of Zhejiang Province, Mental Health Center of Zhejiang Province, Hangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo","family":"Liang","sequence":"additional","affiliation":[{"name":"Department of Mental Health, Tongde Hospital of Zhejiang Province, Mental Health Center of Zhejiang Province, Hangzhou, China"},{"name":"Department of Oncology, Tongde Hospital of Zhejiang Province, Mental Health Center of Zhejiang Province, Hangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,10,9]]},"reference":[{"key":"bibr1-03000605231195154","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596"},{"key":"bibr2-03000605231195154","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2014.01.017"},{"key":"bibr3-03000605231195154","first-page":"Cd000203","volume":"4","author":"Alabed S","year":"2018","journal-title":"Cochrane Database Syst Rev"},{"key":"bibr4-03000605231195154","doi-asserted-by":"publisher","DOI":"10.1111\/head.12246"},{"key":"bibr5-03000605231195154","doi-asserted-by":"publisher","DOI":"10.1002\/mds.20823"},{"key":"bibr6-03000605231195154","doi-asserted-by":"publisher","DOI":"10.1177\/0269881119862535"},{"key":"bibr7-03000605231195154","doi-asserted-by":"publisher","DOI":"10.1177\/070674370505001110"},{"key":"bibr8-03000605231195154","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2019.112491"},{"key":"bibr9-03000605231195154","doi-asserted-by":"publisher","DOI":"10.1002\/wps.20707"},{"key":"bibr10-03000605231195154","doi-asserted-by":"publisher","DOI":"10.1016\/j.ncl.2020.01.004"},{"key":"bibr11-03000605231195154","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnpbp.2004.05.016"},{"key":"bibr12-03000605231195154","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.158.3.360"},{"key":"bibr13-03000605231195154","doi-asserted-by":"publisher","DOI":"10.1002\/1098-2396(200102)39:2<152::AID-SYN6>3.0.CO;2-F"},{"key":"bibr14-03000605231195154","doi-asserted-by":"publisher","DOI":"10.1016\/S0952-3278(96)90143-X"},{"key":"bibr15-03000605231195154","first-page":"97","volume-title":"Benzodiazepine\/GABA receptors and chloride channels: structural and functional properties","author":"Haefely W","year":"1986"},{"key":"bibr16-03000605231195154","first-page":"Cd000203","author":"Alabed S","year":"2011","journal-title":"Cochrane Database Syst Rev"},{"key":"bibr17-03000605231195154","doi-asserted-by":"crossref","unstructured":"Lomanto M. (2010) Baclofen In: Sinatra, Raymond S., Jonathan S. Jahr, and J. Michael Watkins-Pitchford, eds.\n                      The essence of analgesia and analgesics\n                      . Cambridge University Press, 2010, pp 379\u2013382.","DOI":"10.1017\/CBO9780511841378.095"},{"key":"bibr18-03000605231195154","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2020.0249"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03000605231195154","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/03000605231195154","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03000605231195154","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:51:21Z","timestamp":1777459881000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/03000605231195154"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10]]},"references-count":18,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2023,10]]}},"alternative-id":["10.1177\/03000605231195154"],"URL":"https:\/\/doi.org\/10.1177\/03000605231195154","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10]]},"article-number":"03000605231195154"}}