{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T01:19:39Z","timestamp":1784078379218,"version":"3.55.0"},"reference-count":18,"publisher":"SAGE Publications","issue":"9","license":[{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:p>Superficial siderosis of the central nervous system (SSCNS) is a rare disease characterized by iron deposition on the tissue surface of the middle axis system. We report the case of a man in his late 40\u2009s who was admitted to the hospital with ataxia. A physical examination revealed cerebellar ataxia, sensorineural deafness, and bilateral pyramidal tract injury. Susceptibility-weighted magnetic resonance imaging showed linear hypointense signals on the surface of the cerebral hemispheres, sulcus gyrus, lateral ventricles, and cerebellum. The patient underwent treatment with deferiprone, mecobalamin, and vitamin B1, and the symptoms were not aggravated. The patient\u2019s daily living ability was near normal after 1 year of follow-up. A literature review indicated that most SSCNS patients present diverse clinical manifestations. Clinicians may consider SSCNS in patients with hearing impairment and gait ataxia, especially for those receiving anticoagulant therapy and with a history of brain injury or accident.<\/jats:p>","DOI":"10.1177\/03000605231198389","type":"journal-article","created":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T09:35:01Z","timestamp":1694597701000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["A case report of superficial siderosis of the central nervous system and literature review"],"prefix":"10.1177","volume":"51","author":[{"given":"Jian","family":"Huang","sequence":"first","affiliation":[{"name":"Department of Neurology, the First Affiliated Hospital of Gannan Medical University, Ganzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaosheng","family":"Xie","sequence":"additional","affiliation":[{"name":"Department of Neurology, the First Affiliated Hospital of Gannan 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