{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T12:59:11Z","timestamp":1777726751870,"version":"3.51.4"},"reference-count":22,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Construction of Rapid Nucleic Acid Detection Platform for Invasive Fungi","award":["20211214"],"award-info":[{"award-number":["20211214"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:p>Nocardia pseudobrasiliensis is a new taxon constituting an emerging species of human pathogenic Nocardia, which shares morphological features with N. brasiliensis. However, N. pseudobrasiliensis is more invasive and more easily disseminated, and it exhibits distinctive antibiotic susceptibility. Few clinical cases related to N. pseudobrasiliensis infection have been reported, and N. pseudobrasiliensis hydrarthrosis has not been described. Here, we analyzed the case information, diagnostic process, treatment, and prognosis of a patient with N. pseudobrasiliensis hydrarthrosis who received treatment in Zhejiang Provincial People's Hospital. Magnetic resonance imaging showed joint cavity effusion and soft tissue swelling with high signal on proton density-fat saturated images and low signal on T1-weighted images. Oil microscopy revealed abundant acid-fast\u2013positive filaments in hydrarthrosis puncture fluid. The pathogen was identified as N. pseudobrasiliensis by matrix-assisted laser desorption ionization\u2013time of flight mass spectrometry. In contrast to the 100% ciprofloxacin resistance displayed by N. brasiliensis, this clinical isolate of N. pseudobrasiliensis was completely susceptible. In summary, this is the first report of N. pseudobrasiliensis in joint effusion from a patient with arthritis.<\/jats:p>","DOI":"10.1177\/03000605231206959","type":"journal-article","created":{"date-parts":[[2023,12,11]],"date-time":"2023-12-11T23:32:53Z","timestamp":1702337573000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["<i>Nocardia pseudobrasiliensis<\/i>\n                    infection in a patient with arthritis"],"prefix":"10.1177","volume":"51","author":[{"given":"Youqi","family":"Ji","sequence":"first","affiliation":[{"name":"Laboratory Medicine Center, Department of Clinical Laboratory, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China"},{"name":"School of Medical Technology and Information Engineering, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mengyuan","family":"Chen","sequence":"additional","affiliation":[{"name":"Laboratory Medicine Center, Department of Clinical Laboratory, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China"},{"name":"The Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin","family":"Hong","sequence":"additional","affiliation":[{"name":"Laboratory Medicine Center, Department of Clinical Laboratory, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China"},{"name":"Department of Green Pharmaceutical Collaborative Innovation Center, School of Pharmacy, Zhejiang University of Technology, Hangzhou, Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liya","family":"Pan","sequence":"additional","affiliation":[{"name":"Center for Rehabilitation Medicine, Department of Radiology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), Hangzhou, Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dongqing","family":"Cheng","sequence":"additional","affiliation":[{"name":"School of Medical Technology and Information Engineering, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3321-2176","authenticated-orcid":false,"given":"Yumei","family":"Ge","sequence":"additional","affiliation":[{"name":"Laboratory Medicine Center, Department of Clinical Laboratory, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China"},{"name":"School of Medical Technology and Information Engineering, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China"},{"name":"The Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China"},{"name":"Department of Green Pharmaceutical Collaborative Innovation Center, School of Pharmacy, Zhejiang University of Technology, Hangzhou, Zhejiang, China"},{"name":"Center for Rehabilitation Medicine, Department of Radiology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), Hangzhou, Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,12,11]]},"reference":[{"key":"bibr1-03000605231206959","doi-asserted-by":"crossref","first-page":"e0156021","DOI":"10.1128\/spectrum.01560-21","volume":"10","author":"Wang H","year":"2022","journal-title":"Microbiol Spectr"},{"key":"bibr2-03000605231206959","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.19.2.259-282.2006"},{"key":"bibr3-03000605231206959","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01531-13"},{"key":"bibr4-03000605231206959","doi-asserted-by":"publisher","DOI":"10.1099\/00207713-46-1-259"},{"key":"bibr5-03000605231206959","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2014-205262"},{"key":"bibr6-03000605231206959","doi-asserted-by":"publisher","DOI":"10.1177\/2324709620938228"},{"key":"bibr7-03000605231206959","doi-asserted-by":"publisher","DOI":"10.1111\/head.12246"},{"key":"bibr8-03000605231206959","doi-asserted-by":"publisher","DOI":"10.1186\/s12941-022-00511-9"},{"key":"bibr9-03000605231206959","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.33.6.1528-1533.1995"},{"key":"bibr10-03000605231206959","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000002490"},{"key":"bibr11-03000605231206959","first-page":"43","volume":"53","author":"Mangieri NA","year":"2021","journal-title":"Rev Argent Microbiol"},{"key":"bibr12-03000605231206959","first-page":"e6278","volume":"11","author":"Al-Obaydi S","year":"2019","journal-title":"Cureus"},{"key":"bibr13-03000605231206959","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2011.11.016"},{"key":"bibr14-03000605231206959","doi-asserted-by":"publisher","DOI":"10.1007\/s13312-021-2375-3"},{"key":"bibr15-03000605231206959","doi-asserted-by":"publisher","DOI":"10.3343\/alm.2013.33.3.203"},{"key":"bibr16-03000605231206959","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e31816a43bf"},{"key":"bibr17-03000605231206959","doi-asserted-by":"publisher","DOI":"10.1023\/A:1023340624229"},{"key":"bibr18-03000605231206959","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01244-09"},{"key":"bibr19-03000605231206959","doi-asserted-by":"publisher","DOI":"10.1086\/517180"},{"key":"bibr20-03000605231206959","doi-asserted-by":"publisher","DOI":"10.1016\/j.medmal.2013.01.012"},{"key":"bibr21-03000605231206959","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinmicnews.2012.04.002"},{"key":"bibr22-03000605231206959","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01419-17"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03000605231206959","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/03000605231206959","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03000605231206959","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:47:42Z","timestamp":1777459662000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/03000605231206959"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12]]},"references-count":22,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2023,12]]}},"alternative-id":["10.1177\/03000605231206959"],"URL":"https:\/\/doi.org\/10.1177\/03000605231206959","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12]]},"article-number":"03000605231206959"}}