{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T13:13:04Z","timestamp":1777727584736,"version":"3.51.4"},"reference-count":19,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:p>Non-acquired immunodeficiency syndrome-defining cancers (NADCs) are malignancies in persons living with human immunodeficiency virus (PLWHIV) and are not primarily due to the host\u2019s immunodeficiency. There is renewed clinical interest in long-term morbidities in PLWHIV as well as malignancies that occur in this population. We herein describe a 36-year-old woman with a 2-year history of an anal wound and right breast mass. She had been diagnosed with HIV infection prior to the development of these lesions. Clinical and laboratory evaluations led to diagnoses of breast and anal cancers. Chemotherapy and antiretroviral therapy were begun, but the patient discontinued these treatments early and was lost to follow-up. NADCs will continue to be a major clinical issue as the global population ages. This presentation of two NADCs (breast and anal cancers) in a PLWHIV further highlights the burden of multiple malignancies on the depleted health of HIV-infected patients. Early identification and treatment of HIV upon patients\u2019 presentation to cancer care sites and screening for NADCs at HIV\/AIDS care sites are recommended for improved outcomes.<\/jats:p>","DOI":"10.1177\/03000605241245011","type":"journal-article","created":{"date-parts":[[2024,4,12]],"date-time":"2024-04-12T06:58:17Z","timestamp":1712905097000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Multiple carcinomas in a woman with HIV infection: a case report and literature review"],"prefix":"10.1177","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0763-9707","authenticated-orcid":false,"given":"John Adi","family":"Ashindoitiang","sequence":"first","affiliation":[{"name":"Department of Surgery, University of Calabar\/University of Calabar Teaching Hospital, Calabar, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victor Ikechukwu Carnice","family":"Nwagbara","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of Calabar\/University of Calabar Teaching Hospital, Calabar, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7507-4061","authenticated-orcid":false,"given":"Mba Okpan","family":"Ozinko","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of Calabar\/University of Calabar Teaching Hospital, Calabar, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Theophilus Ipeh","family":"Ugbem","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Calabar\/University of Calabar Teaching Hospital, Calabar, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maurice Efana","family":"Asuquo","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of Calabar\/University of Calabar Teaching Hospital, Calabar, 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