{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T22:04:21Z","timestamp":1781215461741,"version":"3.54.1"},"reference-count":17,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:p>Kikuchi\u2013Fujimoto disease (KFD), also known as histiocytic necrotizing lymphadenitis, is a rare, benign condition affecting young Oriental-Asian females. It is characterized by fever and tender cervical lymphadenopathy with an unclear aetiology, and in most longitudinal reviews, KFD occurs before systemic lupus erythematosus (SLE). Herein, the case of a 28-year-old Kuwaiti female without any relevant past medical history, who was simultaneously diagnosed with KFD and SLE following an Ebstein\u2013Barr virus infection, is reported. The patient was treated with oral prednisolone, hydroxychloroquine, cyclosporin, and belimumab and her response was clinically and biochemically favourable. Although KFD is prevalent in Asian populations, it may affect all races. Early diagnosis of KFD is difficult, particularly when simultaneously diagnosed with SLE, but crucial to preventing inappropriate therapy. Clinicians need to know about this rare disease, especially when patients present with fever and swollen lymph nodes, due to a risk of misdiagnosis with tuberculosis or lymphoma, as these are more often thought to be the cause of such symptoms.<\/jats:p>","DOI":"10.1177\/03000605241248884","type":"journal-article","created":{"date-parts":[[2024,5,7]],"date-time":"2024-05-07T11:17:22Z","timestamp":1715080642000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Kikuchi-Fujimoto disease, simultaneously diagnosed with systemic lupus erythematosus in an Arabic female: an agonizing combination"],"prefix":"10.1177","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6753-3811","authenticated-orcid":false,"given":"Wesam","family":"Gouda","sequence":"first","affiliation":[{"name":"Department of Rheumatology, Faculty of Medicine, Al Azhar University, Egypt"},{"name":"Rheumatology Unit, Al\u2010Sabah Hospital, Kuwait"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Faisal","family":"Alsaqabi","sequence":"additional","affiliation":[{"name":"Rheumatology Unit, Al\u2010Sabah Hospital, Kuwait"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8824-5640","authenticated-orcid":false,"given":"Maryam","family":"Almurshed","sequence":"additional","affiliation":[{"name":"Department of Pathology, Al\u2010Sabah Hospital, Kuwait"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashraf A.","family":"Mostafa","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Faculty of Medicine, Al Azhar University, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anwar","family":"Albasri","sequence":"additional","affiliation":[{"name":"Rheumatology Unit, Al\u2010Sabah Hospital, Kuwait"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3849-6852","authenticated-orcid":false,"given":"Ahmed","family":"Negm","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Faculty of Medicine, Al Azhar University, Egypt"},{"name":"Rheumatology Unit, Medical Affairs Department, Dubai Hospital, Dubai, UAE"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Md Asiful","family":"Islam","sequence":"additional","affiliation":[{"name":"WHO Collaborating Centre for Global Women\u2019s Health, Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"Kamal","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Faculty of Medicine, Al Azhar University, Egypt"},{"name":"Faculty of Medicine, Taibah University, Medina, Saudi 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