{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T14:35:22Z","timestamp":1793370922248,"version":"4.5.0"},"reference-count":18,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Hospital Pharmacy of Zhejiang Pharmaeutical Association","award":["No. 2022ZYY37"],"award-info":[{"award-number":["No. 2022ZYY37"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:p>Sodium-glucose cotransporter-2 (SGLT2) inhibitors are extensively used in the management of heart failure because of their cardiovascular benefits. Adverse drug reactions associated with dapagliflozin include diabetic ketoacidosis, fungal infections, and increased blood glucose concentrations. However, abnormal uterine bleeding is not a known side effect of dapagliflozin. We report a 75-year-old Chinese woman with dilated cardiomyopathy and chronic heart failure who experienced abnormal uterine bleeding while taking dapagliflozin. Notably, cessation of dapagliflozin administration resulted in the disappearance of uterine bleeding. These findings suggest that dapagliflozin possesses additional potential mechanisms, but these mechanisms require further investigation. Furthermore, healthcare professionals should remain vigilant regarding the occurrence of uterine bleeding when prescribing dapagliflozin.<\/jats:p>","DOI":"10.1177\/03000605241271750","type":"journal-article","created":{"date-parts":[[2024,8,24]],"date-time":"2024-08-24T03:18:17Z","timestamp":1724469497000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Dapagliflozin-induced abnormal uterine bleeding in a patient with dilated cardiomyopathy and chronic heart failure: a case report"],"prefix":"10.1177","volume":"52","author":[{"given":"Shikun","family":"Gong","sequence":"first","affiliation":[{"name":"Department of Cardiovascular, Beilun District People\u2019s Hospital (Zhejiang University School of Medicine First Affiliated Hospital Beilun Branch), Ningbo, Zhejiang 315800, 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