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A 36-year-old woman was admitted with a complaint of pain in her right mid-thigh following low-energy trauma. She had been taking alendronate for more than 15 years. X-rays indicated a fracture of the right femoral shaft. The patient was treated with proximal femoral nail antirotation (PFNA) fixation. This case highlights concerns regarding long-term bisphosphonate therapy and its potential complications.<\/jats:p>","DOI":"10.1177\/03000605241286650","type":"journal-article","created":{"date-parts":[[2024,10,25]],"date-time":"2024-10-25T04:42:18Z","timestamp":1729831338000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Long-term administration of alendronate sodium caused an atypical femoral shaft fracture in a 36-year-old woman: a case report and literature review"],"prefix":"10.1177","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-3461-1201","authenticated-orcid":false,"given":"Wenyu","family":"Duan","sequence":"first","affiliation":[{"name":"BaoTou Medical College, Inner Mongolia University of Science and Technology, BaoTou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maochang","family":"Qiang","sequence":"additional","affiliation":[{"name":"BaoTou Medical College, Inner Mongolia University of Science and Technology, BaoTou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haidong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Orthopaedic Trauma Ward 1, The First Affiliated Hospital of BaoTou Medical College, Inner Mongolia University of Science and Technology, BaoTou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dongming","family":"Zhou","sequence":"additional","affiliation":[{"name":"Orthopaedic Trauma Ward 1, The First Affiliated Hospital of BaoTou Medical College, Inner Mongolia University of Science and Technology, BaoTou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,10,25]]},"reference":[{"key":"bibr1-03000605241286650","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1001086"},{"key":"bibr2-03000605241286650","doi-asserted-by":"publisher","DOI":"10.1016\/j.jot.2016.06.029"},{"key":"bibr3-03000605241286650","doi-asserted-by":"publisher","DOI":"10.1038\/nrendo.2015.71"},{"key":"bibr4-03000605241286650","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2014-206319"},{"key":"bibr5-03000605241286650","doi-asserted-by":"publisher","DOI":"10.1186\/s12891-023-06327-8"},{"key":"bibr6-03000605241286650","first-page":"251","volume":"13","author":"Patel V","year":"2013","journal-title":"J Musculoskelet Neuronal Interact"},{"key":"bibr7-03000605241286650","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-010-1453-5"},{"key":"bibr8-03000605241286650","doi-asserted-by":"publisher","DOI":"10.1007\/s00264-013-2259-9"},{"key":"bibr9-03000605241286650","doi-asserted-by":"publisher","DOI":"10.1308\/003588415X14181254789321"},{"key":"bibr10-03000605241286650","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2017-222129"},{"key":"bibr11-03000605241286650","first-page":"e4544120230918","volume":"15","author":"Febrian Kunta Adjie R","year":"2023","journal-title":"Cureus"},{"key":"bibr12-03000605241286650","doi-asserted-by":"publisher","DOI":"10.1186\/s13256-015-0590-z"},{"key":"bibr13-03000605241286650","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2013.12.027"},{"key":"bibr14-03000605241286650","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbspin.2017.12.001"},{"key":"bibr15-03000605241286650","doi-asserted-by":"publisher","DOI":"10.1097\/gme.0b013e318260143d"},{"key":"bibr16-03000605241286650","doi-asserted-by":"publisher","DOI":"10.3109\/17453674.2015.1004149"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03000605241286650","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/03000605241286650","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03000605241286650","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:49:02Z","timestamp":1777459742000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/03000605241286650"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":16,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2024,10]]}},"alternative-id":["10.1177\/03000605241286650"],"URL":"https:\/\/doi.org\/10.1177\/03000605241286650","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10]]},"article-number":"03000605241286650"}}