{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T13:09:49Z","timestamp":1777727389960,"version":"3.51.4"},"reference-count":36,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100012902","name":"Saint Paul\u2019s Hospital Millennium Medical College","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100012902","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Asymptomatic peptic ulcer disease (PUD) is frequently overlooked in patients with cirrhosis, who are at increased risk for gastrointestinal complications that can lead to increased morbidity and mortality. We aimed to determine the prevalence and associated factors of asymptomatic PUD identified during screening endoscopy in patients with cirrhosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a retrospective cross-sectional study among patients with cirrhosis at St. Paul\u2019s Hospital Millennium Medical College in Ethiopia. Data were collected using a structured questionnaire from patients\u2019 medical charts. A logistic regression model was used to identify predictors of peptic ulcer.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>This study included 296 patients, revealing that 19.6% had PUD (95% confidence interval: 13.5\u201326.4). Significant associations were found between peptic ulcer and Helicobacter pylori infection, moderate and heavy alcohol consumption, and Child\u2013Pugh class C cirrhosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>We found that patients with liver cirrhosis are more likely to have asymptomatic peptic ulcers. Asymptomatic PUD was linked to H. pylori infection, greater alcohol consumption, and Child\u2013Pugh class C liver disease, highlighting the need for targeted prevention and management strategies to reduce morbidity in patients with cirrhosis, such as eradication therapy for H. pylori and counseling on alcohol use.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/03000605241305258","type":"journal-article","created":{"date-parts":[[2024,12,18]],"date-time":"2024-12-18T05:12:13Z","timestamp":1734498733000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Epidemiology of asymptomatic peptic ulcer disease diagnosed during screening endoscopy in patients with cirrhosis"],"prefix":"10.1177","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-5397-9326","authenticated-orcid":false,"given":"Girma Deshimo","family":"Lema","sequence":"first","affiliation":[{"name":"School of Medicine, Asrat Woldeyes Health Science Campus, Debre Berhan University, Debre Berhan, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enguday Demeke","family":"Gebeyaw","sequence":"additional","affiliation":[{"name":"School of Public Health, Asrat Woldeyes Health Science Campus, Debre Berhan University, Debre Berhan, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,12,18]]},"reference":[{"key":"bibr1-03000605241305258","doi-asserted-by":"publisher","DOI":"10.1097\/00042737-200207000-00002"},{"key":"bibr2-03000605241305258","doi-asserted-by":"publisher","DOI":"10.1080\/00325481.2020.1795485"},{"key":"bibr3-03000605241305258","doi-asserted-by":"publisher","DOI":"10.1016\/0168-8278(95)80219-3"},{"key":"bibr4-03000605241305258","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.1998.00711.x"},{"key":"bibr5-03000605241305258","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2012.05140.x"},{"key":"bibr6-03000605241305258","doi-asserted-by":"publisher","DOI":"10.1007\/BF02088737"},{"key":"bibr7-03000605241305258","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2005.02507.x"},{"key":"bibr8-03000605241305258","first-page":"763","volume":"13","author":"Pienkowski P","year":"1989","journal-title":"Gastroenterol Clin Biol"},{"key":"bibr9-03000605241305258","doi-asserted-by":"publisher","DOI":"10.1007\/BF01536055"},{"key":"bibr10-03000605241305258","doi-asserted-by":"publisher","DOI":"10.1016\/S1590-8658(03)00029-X"},{"key":"bibr11-03000605241305258","doi-asserted-by":"publisher","DOI":"10.3904\/kjim.2008.23.1.16"},{"key":"bibr12-03000605241305258","doi-asserted-by":"publisher","DOI":"10.1007\/BF01345294"},{"key":"bibr13-03000605241305258","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(97)80459-X"},{"key":"bibr14-03000605241305258","first-page":"26","volume":"4","author":"Kirchner GI","year":"2011","journal-title":"Int J Clin Exp Med"},{"key":"bibr15-03000605241305258","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(95)70044-7"},{"key":"bibr16-03000605241305258","first-page":"451","volume":"32","author":"Voulgaris T","year":"2019","journal-title":"Ann Gastroenterol"},{"key":"bibr17-03000605241305258","first-page":"395","volume":"46","author":"Zullo A","year":"1999","journal-title":"Hepatogastroenterology"},{"key":"bibr18-03000605241305258","doi-asserted-by":"publisher","DOI":"10.1023\/A:1018899506271"},{"key":"bibr19-03000605241305258","first-page":"169","author":"Wu CS","year":"1998","journal-title":"Korean Journal of Gastrointestinal Endoscopy"},{"key":"bibr20-03000605241305258","first-page":"2387","volume":"56","author":"Fujiwara Y","year":"1998","journal-title":"Nihon Rinsho"},{"key":"bibr21-03000605241305258","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2012.05225.x"},{"key":"bibr22-03000605241305258","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.1998.00711.x"},{"key":"bibr23-03000605241305258","doi-asserted-by":"publisher","DOI":"10.4103\/1755-6783.177379"},{"key":"bibr24-03000605241305258","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-147-8-200710160-00010"},{"key":"bibr25-03000605241305258","first-page":"219","volume":"38","author":"Piano MR.","year":"2017","journal-title":"Alcohol Res"},{"key":"bibr26-03000605241305258","volume-title":"Use Of The Child Pugh Score In Liver Disease. 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