{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T22:23:33Z","timestamp":1793917413236,"version":"4.8.0"},"reference-count":15,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:p>\n                    Some subtypes of acute myeloid leukemia share morphologic, immunophenotypic, and clinical features of acute promyelocytic leukemia but lack a promyelocytic leukemia\u2013retinoic acid receptor alpha fusion gene. Herein, we present a case of acute myeloid leukemia with morphological and clinical features resembling those of acute promyelocytic leukemia, carrying the rare DEK::NUP214 fusion gene and presenting with sweet syndrome as the initial manifestation. In our case, the patient with acute myeloid leukemia carrying\n                    <jats:italic toggle=\"yes\">DEK::NUP214<\/jats:italic>\n                    fusion exhibited highly active bone marrow proliferation, with increased basophil and promyelocyte counts. To the best of our knowledge, this is the first reported case of acute promyelocytic leukemia\u2013like acute myeloid leukemia carrying\n                    <jats:italic toggle=\"yes\">DEK::NUP214<\/jats:italic>\n                    fusion.\n                  <\/jats:p>","DOI":"10.1177\/03000605251327476","type":"journal-article","created":{"date-parts":[[2025,3,26]],"date-time":"2025-03-26T17:46:18Z","timestamp":1743011178000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Acute myeloid leukemia with\n                    <i>DEK::NUP214<\/i>\n                    fusion resembling acute promyelocytic leukemia, initially presenting as sweet syndrome: A case report and literature review"],"prefix":"10.1177","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-3605-1146","authenticated-orcid":false,"given":"Huan","family":"Liu","sequence":"first","affiliation":[{"name":"Qingdao University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guo-Xia","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, Jinan Stomatological Hospital, Jinan, Shandong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng-Hai","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, Qingdao Municipal Hospital, Qingdao, Shandong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shu-Guo","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, Qingdao Municipal Hospital, Qingdao, Shandong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,3,26]]},"reference":[{"key":"e_1_3_9_2_2","doi-asserted-by":"publisher","DOI":"10.1177\/1203475417690719"},{"key":"e_1_3_9_3_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2003.04.036"},{"key":"e_1_3_9_4_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2022016867"},{"key":"e_1_3_9_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41375-022-01613-1"},{"key":"e_1_3_9_6_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-03-209262"},{"key":"e_1_3_9_7_2","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1038\/s41379-021-00741-w","article-title":"Myelodysplastic syndrome with t(6;9)(p22;q34.1)\/DEK-NUP214 better classified as acute myeloid leukemia? A multicenter study of 107 cases","volume":"34","author":"Fang H","year":"2021","unstructured":"Fang H, Yabe M, Zhang X, et\u00a0al. Myelodysplastic syndrome with t(6;9)(p22;q34.1)\/DEK-NUP214 better classified as acute myeloid leukemia? A multicenter study of 107 cases. Mod Pathol 2021; 34: 1143\u20131152.","journal-title":"Mod Pathol"},{"key":"e_1_3_9_8_2","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1309\/5DGB59KQA527PD47","article-title":"Acute myeloid leukemia with t(6;9)(p23;q34) is associated with dysplasia and a high frequency of flt3 gene mutations","volume":"122","author":"Oyarzo MP","year":"2004","unstructured":"Oyarzo MP, Lin P, Glassman A, et\u00a0al. Acute myeloid leukemia with t(6;9)(p23;q34) is associated with dysplasia and a high frequency of flt3 gene mutations. 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Leukemia 2006; 20: 1295\u20131297.","journal-title":"Leukemia"},{"key":"e_1_3_9_10_2","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1111\/ijlh.12641","article-title":"Clinicopathologic and molecular characterization of myeloid neoplasms with isolated t(6;9)(p23;q34)","volume":"39","author":"Visconte V","year":"2017","unstructured":"Visconte V, Shetty S, Przychodzen B, et\u00a0al. Clinicopathologic and molecular characterization of myeloid neoplasms with isolated t(6;9)(p23;q34). Int J Lab Hematol 2017; 39: 409\u2013417.","journal-title":"Int J Lab Hematol"},{"key":"e_1_3_9_11_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-03-0867"},{"key":"e_1_3_9_12_2","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1038\/s41375-020-0920-z","article-title":"The clinical impact of PTPN11 mutations in adults with acute myeloid leukemia","volume":"35","author":"Alfayez M","year":"2021","unstructured":"Alfayez M, Issa GC, Patel KP, et\u00a0al. The clinical impact of PTPN11 mutations in adults with acute myeloid leukemia. Leukemia 2021; 35: 691\u2013700.","journal-title":"Leukemia"},{"key":"e_1_3_9_13_2","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/S0190-9622(94)70215-2","article-title":"Sweets-syndrome (acute febrile neutrophilic dermatosis)","volume":"31","author":"Von den Driesch P.","year":"1994","unstructured":"Von den Driesch P. Sweets-syndrome (acute febrile neutrophilic dermatosis). J Am Acad Dermatol 1994; 31: 535\u2013556.","journal-title":"J Am Acad Dermatol"},{"key":"e_1_3_9_14_2","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1016\/0002-9343(87)90229-4","article-title":"Sweet\u2019s syndrome and malignancy","volume":"82","author":"Cohen PR","year":"1987","unstructured":"Cohen PR, Kurzrock R. Sweet\u2019s syndrome and malignancy. Am J Med 1987; 82: 1220\u20131226.","journal-title":"Am J Med"},{"key":"e_1_3_9_15_2","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/j.clml.2014.12.009","article-title":"Characteristics of sweet syndrome in patients with acute myeloid leukemia","volume":"15","author":"Kazmi SM","year":"2015","unstructured":"Kazmi SM, Pemmaraju N, Patel KP, et\u00a0al. Characteristics of sweet syndrome in patients with acute myeloid leukemia. 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