{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T12:42:34Z","timestamp":1790858554059,"version":"4.1.0"},"reference-count":56,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"This research was funded by the Central Funds Guiding the Local Science and Tech-nology Development\uff1b2022; China","award":["grant number Z20221343023"],"award-info":[{"award-number":["grant number Z20221343023"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:p>Successful embryo implantation relies on embryo quality, endometrial receptivity, and the synchronized development of both. In recent years, methods for assessing endometrial receptivity have considerably advanced, shifting from traditional imaging techniques to modern molecular biology approaches. The evaluation of endometrial thickness, morphology, subendometrial blood flow, and peristalsis before implantation has become less prominent, whereas molecular markers such as pinopodes, integrin \u03b1v\u03b23, its ligand osteopontin, and homologous box gene A10 are widely used in clinical practice for assessing endometrial receptivity. To provide a comprehensive overview, this narrative review systematically searched PubMed and Web of Science for studies on endometrial receptivity assessment in infertile women over the past two decades, with a focus on both clinical and experimental research. This narrative review has examined recent advancements in morphological markers, endometrial receptivity\u2013related genes, endometrial microbiota, and other emerging indicators, emphasizing their potential in optimizing embryo implantation and improving the success rates of assisted reproductive technologies. Notably, endometrial receptivity array testing and uterine microbiome analysis have gained substantial attention for their potential in personalized diagnosis and treatment. This review aims to provide scientific insights for precise infertility diagnostics and individualized treatment strategies while offering recommendations for future research development.<\/jats:p>","DOI":"10.1177\/03000605251328893","type":"journal-article","created":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T18:04:52Z","timestamp":1745949892000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":14,"title":["Molecular and biological markers for assessing endometrial receptivity in infertile women: A narrative review"],"prefix":"10.1177","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-7088-4790","authenticated-orcid":false,"given":"Junfeng","family":"Li","sequence":"first","affiliation":[{"name":"Henan Key Laboratory of Fertility Protection and Aristogenesis; Department of Reproductive Center, Luohe Central Hospital, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hange","family":"Liu","sequence":"additional","affiliation":[{"name":"Luohe Central Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin","family":"Lim","sequence":"additional","affiliation":[{"name":"Program in Biology, Division of Biology and Medicine, Brown University, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hang","family":"Xing","sequence":"additional","affiliation":[{"name":"The Alpert Medical School of Brown University, Department of Pediatrics, Women &amp; Infants Hospital of Rhode Island, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Chen","sequence":"additional","affiliation":[{"name":"Henan Key Laboratory of Fertility Protection and Aristogenesis; Department of Reproductive Center, Luohe Central Hospital, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaozhe","family":"Yang","sequence":"additional","affiliation":[{"name":"Henan Key Laboratory of Fertility Protection and Aristogenesis; Department of Reproductive Center, Luohe Central Hospital, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiuhong","family":"Fu","sequence":"additional","affiliation":[{"name":"Henan Key Laboratory of Fertility Protection and Aristogenesis; Department of Reproductive Center, Luohe Central Hospital, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,4,29]]},"reference":[{"key":"e_1_3_6_2_2","volume-title":"Infertility prevalence estimates, 1990\u20132021","year":"2023","unstructured":"Infertility prevalence estimates, 1990\u20132021. Geneva: World Health Organization, 2023."},{"key":"e_1_3_6_3_2","first-page":"487","article-title":"The past, present, and future of embryo selection in in vitro fertilization: frontiers in reproduction conference","volume":"84","author":"Wang SX.","year":"2011","unstructured":"Wang SX. The past, present, and future of embryo selection in in vitro fertilization: frontiers in reproduction conference. Yale J Biol Med 2011; 84: 487\u2013490.","journal-title":"Yale J Biol Med"},{"key":"e_1_3_6_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmy044"},{"key":"e_1_3_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2019.02.009"},{"key":"e_1_3_6_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2019.110644"},{"key":"e_1_3_6_7_2","doi-asserted-by":"publisher","DOI":"10.1080\/15384101.2022.2075198"},{"key":"e_1_3_6_8_2","doi-asserted-by":"publisher","DOI":"10.3390\/jpm13050749"},{"key":"e_1_3_6_9_2","doi-asserted-by":"publisher","DOI":"10.1186\/s41073-019-0064-8"},{"key":"e_1_3_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(88)90084-1"},{"key":"e_1_3_6_11_2","doi-asserted-by":"publisher","DOI":"10.1080\/09513590.2019.1653562"},{"key":"e_1_3_6_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(99)00605-6"},{"key":"e_1_3_6_13_2","doi-asserted-by":"publisher","DOI":"10.3390\/medicina54050069"},{"key":"e_1_3_6_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2017.07.006"},{"key":"e_1_3_6_15_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21061973"},{"key":"e_1_3_6_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(01)01993-8"},{"key":"e_1_3_6_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmn052"},{"key":"e_1_3_6_18_2","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2023.1158515"},{"key":"e_1_3_6_19_2","doi-asserted-by":"publisher","DOI":"10.1530\/REP-20-0273"},{"key":"e_1_3_6_20_2","doi-asserted-by":"publisher","DOI":"10.1093\/molehr\/gan029"},{"key":"e_1_3_6_21_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7580.2008.01034.x"},{"key":"e_1_3_6_22_2","doi-asserted-by":"publisher","DOI":"10.1093\/hropen\/hoab034"},{"key":"e_1_3_6_23_2","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7827-9-29"},{"key":"e_1_3_6_24_2","doi-asserted-by":"publisher","DOI":"10.5582\/ddt.2023.01016"},{"key":"e_1_3_6_25_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-86956-y"},{"key":"e_1_3_6_26_2","doi-asserted-by":"publisher","DOI":"10.1007\/s43032-021-00629-9"},{"key":"e_1_3_6_27_2","doi-asserted-by":"publisher","DOI":"10.1387\/ijdb.190120dm"},{"key":"e_1_3_6_28_2","doi-asserted-by":"publisher","DOI":"10.1177\/1933719114549846"},{"key":"e_1_3_6_29_2","doi-asserted-by":"publisher","DOI":"10.1111\/aji.13702"},{"key":"e_1_3_6_30_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2013-1429"},{"key":"e_1_3_6_31_2","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/317586"},{"key":"e_1_3_6_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2016.09.016"},{"key":"e_1_3_6_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.rbmo.2024.104381"},{"key":"e_1_3_6_34_2","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmaa051"},{"key":"e_1_3_6_35_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2022.03.053"},{"key":"e_1_3_6_36_2","doi-asserted-by":"publisher","DOI":"10.1210\/endo.141.12.7855"},{"key":"e_1_3_6_37_2","doi-asserted-by":"publisher","DOI":"10.1210\/endocr\/bqab169"},{"key":"e_1_3_6_38_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2005.01.033"},{"key":"e_1_3_6_39_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-022-06450-2"},{"key":"e_1_3_6_40_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2015.12.015"},{"key":"e_1_3_6_41_2","doi-asserted-by":"publisher","DOI":"10.1055\/a-1056-3148"},{"key":"e_1_3_6_42_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2010.04.063"},{"key":"e_1_3_6_43_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2012.09.046"},{"key":"e_1_3_6_44_2","doi-asserted-by":"publisher","DOI":"10.1002\/rmb2.12041"},{"key":"e_1_3_6_45_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-019-01535-5"},{"key":"e_1_3_6_46_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2020.07.058"},{"key":"e_1_3_6_47_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2024.1369317"},{"key":"e_1_3_6_48_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-018-1125-5"},{"key":"e_1_3_6_49_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms25010622"},{"key":"e_1_3_6_50_2","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dead274"},{"key":"e_1_3_6_51_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2016.09.075"},{"key":"e_1_3_6_52_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-017-00901-0"},{"key":"e_1_3_6_53_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2024.1351540"},{"key":"e_1_3_6_54_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-020-01878-4"},{"key":"e_1_3_6_55_2","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deu292"},{"key":"e_1_3_6_56_2","doi-asserted-by":"publisher","DOI":"10.1111\/aji.70005"},{"key":"e_1_3_6_57_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2020.01.031"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03000605251328893","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/03000605251328893","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03000605251328893","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:47:18Z","timestamp":1777459638000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/03000605251328893"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":56,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["10.1177\/03000605251328893"],"URL":"https:\/\/doi.org\/10.1177\/03000605251328893","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4]]},"article-number":"03000605251328893"}}