{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T13:18:06Z","timestamp":1793798286860,"version":"4.6.1"},"reference-count":20,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:p>Neurofibromatosis type 1 is an autosomal dominant disorder. The vasculopathy of neurofibromatosis type 1 may rarely comprise stenosis, occlusion, aneurysm, pseudoaneurysm, and arteriovenous deformity, and it often presents as rupture of an undiagnosed lesion, which highly increases mortality in young patients with neurofibromatosis type 1. A female patient in her early 30s who had neurofibromatosis type 1 presented to our hospital with extensive and progressive bleeding of a ruptured renal artery pseudoaneurysm caused by trauma. Complete total embolization of the renal artery was performed using several microcoils and a mixture of n-butyl cyanoacrylate and iodized oil. Despite combined endovascular and surgical management tailored to the patient\u2019s condition, she died from uncontrolled bleeding. Endovascular treatment is widely regarded as a safe and less invasive option for managing vascular complications in neurofibromatosis type 1. However, it may be insufficient in rapidly progressive cases. Considering the vascular fragility and recurrence of hemorrhagic shock, earlier surgical intervention, including nephrectomy, should have been more strongly considered. This case highlights the limitations of repeated endovascular management alone and suggests that prompt surgical exploration is warranted when pseudoaneurysm rupture is suspected, even in seemingly stable patients. Ultimately, this case underscores the need for heightened clinical vigilance and early surgical decision-making in the treatment of neurofibromatosis type 1 and rapidly evolving vascular injuries.<\/jats:p>","DOI":"10.1177\/03000605251335853","type":"journal-article","created":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T18:04:52Z","timestamp":1745949892000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Renal artery rupture with lethal outcome in a patient with neurofibromatosis type 1: Case report and review of literature"],"prefix":"10.1177","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6264-7171","authenticated-orcid":false,"given":"Jisun","family":"Lee","sequence":"first","affiliation":[{"name":"College of Medicine, Chungbuk National University"},{"name":"Chungbuk National University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2162-419X","authenticated-orcid":false,"given":"Yook","family":"Kim","sequence":"additional","affiliation":[{"name":"College of Medicine, Chungbuk National University"},{"name":"Chungbuk National University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,4,29]]},"reference":[{"key":"e_1_3_7_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1988.00520290115023"},{"key":"e_1_3_7_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/00125817-200205000-00002"},{"key":"e_1_3_7_4_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-0004.2000.580501.x"},{"key":"e_1_3_7_5_2","doi-asserted-by":"publisher","DOI":"10.1086\/320121"},{"key":"e_1_3_7_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11604-009-0334-3"},{"key":"e_1_3_7_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2010.04.031"},{"key":"e_1_3_7_8_2","doi-asserted-by":"publisher","DOI":"10.1177\/1538574413495465"},{"key":"e_1_3_7_9_2","doi-asserted-by":"publisher","DOI":"10.1177\/1538574418800557"},{"key":"e_1_3_7_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/head.12246"},{"key":"e_1_3_7_11_2","first-page":"693","article-title":"Neurofibromatosis with major arterial involvement: a clinicopathologic study","volume":"5","author":"Salyer WR","year":"1974","unstructured":"Salyer WR, Salyer DC. 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