{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T15:38:07Z","timestamp":1792683487639,"version":"4.5.0"},"reference-count":24,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100017575","name":"\u0110\u1ea1i h\u1ecdc Hu\u1ebf","doi-asserted-by":"publisher","award":["DHH2023-04-198 and NCTB.DHH.2025.07"],"award-info":[{"award-number":["DHH2023-04-198 and NCTB.DHH.2025.07"]}],"id":[{"id":"10.13039\/501100017575","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aimed to evaluate oxidative stress in follicular fluid by measuring oxidation\u2013reduction potential and determine its correlation with embryo quality in patients with diminished ovarian reserve.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This cross-sectional study included 134 patients with diminished ovarian reserve and 82 patients with normal ovarian reserve. Follicular fluid samples were collected from each patient via transvaginal aspiration under ultrasound guidance. Oxidation\u2013reduction potential was measured using the Male Infertility Oxidative system, following the manufacturer\u2019s protocol.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The levels of anti-M\u00fcllerian hormone, number of oocytes retrieved, rate of blastocyst formation, and rate of high-quality embryos were significantly lower in the diminished ovarian reserve group than in the normal ovarian reserve group. Correlation analysis revealed that oxidation\u2013reduction potential values had a negative correlation with the number of oocytes retrieved (r\u2009=\u2009\u22120.262, p\u2009=\u20090.002), rate of mature oocytes (r\u2009=\u2009\u22120.260, p\u2009=\u20090.002), and rate of normal fertilization (r\u2009=\u2009\u22120.207, p\u2009=\u20090.016); however, these values showed a positive correlation with the duration of ovarian stimulation (r\u2009=\u20090.186, p\u2009=\u20090.031).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Oxidative stress in follicular fluid correlates with a small number of oocytes retrieved, lower proportion of mature oocytes, and lower rate of normal fertilization in patients with diminished ovarian reserve.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/03000605251349926","type":"journal-article","created":{"date-parts":[[2025,6,16]],"date-time":"2025-06-16T10:18:21Z","timestamp":1750069101000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Does diminished ovarian reserve impact oxidation\u2013reduction potential in follicular fluid?"],"prefix":"10.1177","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6225-3108","authenticated-orcid":false,"given":"Minh Tam","family":"Le","sequence":"first","affiliation":[{"name":"Center for Reproductive Endocrinology and Infertility, Hue University of Medicine and Pharmacy, Vietnam"},{"name":"Department of OBGYN, Hue University of Medicine and Pharmacy, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nguyen Dac","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Center for Reproductive Endocrinology and Infertility, Hue University of Medicine and Pharmacy, Vietnam"},{"name":"Department of OBGYN, Hue University of Medicine and Pharmacy, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong Nhan Thi","family":"Dang","sequence":"additional","affiliation":[{"name":"Center for Reproductive Endocrinology and Infertility, Hue University of Medicine and Pharmacy, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quoc Huy Vu","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of OBGYN, Hue University of Medicine and Pharmacy, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,6,16]]},"reference":[{"key":"e_1_3_8_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2004.06.013"},{"key":"e_1_3_8_3_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13048-017-0342-3"},{"key":"e_1_3_8_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cca.2022.11.003"},{"key":"e_1_3_8_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cyto.2016.12.020"},{"key":"e_1_3_8_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1472-6483(10)61174-1"},{"key":"e_1_3_8_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/molehr\/5.5.409"},{"key":"e_1_3_8_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2003.11.021"},{"key":"e_1_3_8_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deg450"},{"key":"e_1_3_8_10_2","doi-asserted-by":"publisher","DOI":"10.1530\/REP-21-0022"},{"key":"e_1_3_8_11_2","first-page":"449","article-title":"Follicular fluid oxidative stress biomarkers and ART outcomes in PCOS women undergoing in vitro fertilization: a cross-sectional study","volume":"19","author":"Gongadashetti K","year":"2021","unstructured":"Gongadashetti K, Gupta P, Dada R, et\u00a0al. Follicular fluid oxidative stress biomarkers and ART outcomes in PCOS women undergoing in vitro fertilization: a cross-sectional study. Int J Reprod Biomed 2021; 19: 449\u2013456.","journal-title":"Int J Reprod Biomed"},{"key":"e_1_3_8_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-020-02014-y"},{"key":"e_1_3_8_13_2","first-page":"582","article-title":"Oxidative stress statues in serum and follicular fluid of women with endometriosis","volume":"18","author":"Nasiri N","year":"2017","unstructured":"Nasiri N, Moini A, Eftekhari-Yazdi P, et\u00a0al. Oxidative stress statues in serum and follicular fluid of women with endometriosis. 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