{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T13:21:12Z","timestamp":1777728072184,"version":"3.51.4"},"reference-count":18,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:p>\n                    Primary ciliary dyskinesia is a rare autosomal recessive disorder that impairs mucociliary clearance and predisposes children to chronic respiratory infections. Invasive fungal infections caused by\n                    <jats:italic toggle=\"yes\">Lichtheimia (Absidia) corymbifera<\/jats:italic>\n                    are typically confined to profoundly immunocompromised hosts and are exceptionally uncommon in patients without systemic immunosuppression. We report the case of a 6-year-old boy with genetically confirmed primary ciliary dyskinesia (C3orf67 mutation) and right\u2013middle-lobe bronchiectasis who developed persistent cough and increased sputum production. High-resolution chest computed tomography demonstrated right\u2013lower-lobe consolidation and segmental atelectasis. Bronchoalveolar lavage microscopy revealed broad, aseptate\/pauci-septate hyphae, and the culture yielded\n                    <jats:italic toggle=\"yes\">L. corymbifera<\/jats:italic>\n                    , establishing the diagnosis of pulmonary mucormycosis. The child received intravenous liposomal amphotericin B for 18 days, followed by oral azole step-down therapy, resulting in complete clinical and radiological recovery. This case expands the spectrum of invasive mucormycosis to include pediatric patients with primary ciliary dyskinesia in the absence of classical immunosuppressive risk factors. Early bronchoscopy, mold-directed culture, and prompt antifungal therapy, supported by multidisciplinary care, are critical for favorable outcomes.\n                  <\/jats:p>","DOI":"10.1177\/03000605251381480","type":"journal-article","created":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T03:34:52Z","timestamp":1763004892000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Beyond bacteria and breaking the norm: Pulmonary mucormycosis due to\n                    <i>Absidia corymbifera<\/i>\n                    in a child with primary ciliary dyskinesia"],"prefix":"10.1177","volume":"53","author":[{"given":"Abdulrahman O","family":"Alghamdi","sequence":"first","affiliation":[{"name":"Pediatric Department, Alhada Armed Forces Hospital, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fawzyh J","family":"AlKhadidi","sequence":"additional","affiliation":[{"name":"Pediatric Department, Alhada Armed Forces Hospital, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdulraouf H","family":"Alawur","sequence":"additional","affiliation":[{"name":"Pediatric Department, Alhada Armed Forces Hospital, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Safiya","family":"Alkhaldi","sequence":"additional","affiliation":[{"name":"Pediatric Department, Alhada Armed Forces Hospital, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lura","family":"Habib","sequence":"additional","affiliation":[{"name":"Pediatric Department, Alhada Armed Forces Hospital, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roaa","family":"Alharbe","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Alhada Armed Forces Hospital, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdulelah S","family":"Algethami","sequence":"additional","affiliation":[{"name":"Pediatric Department, King Salman Specialized Hospital Ministry of National Guard, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nejood M","family":"Aljaed","sequence":"additional","affiliation":[{"name":"Pediatric Department, Alhada Armed Forces Hospital, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salma AS","family":"Abosabie","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Julius-Maximilians-Universit\u00e4t W\u00fcrzburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara A","family":"Abosabie","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8535-3838","authenticated-orcid":false,"given":"Naglaa M","family":"Kamal","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Cairo University, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,11,12]]},"reference":[{"key":"e_1_3_7_2_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0035-1546748"},{"key":"e_1_3_7_3_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200303-365OC"},{"key":"e_1_3_7_4_2","doi-asserted-by":"publisher","DOI":"10.1513\/pats.201103-028SD"},{"key":"e_1_3_7_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.mph.0000155861.38641.ca"},{"key":"e_1_3_7_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2009.02975.x"},{"key":"e_1_3_7_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cir866"},{"key":"e_1_3_7_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/myc.12239"},{"key":"e_1_3_7_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-017-0991-6"},{"key":"e_1_3_7_10_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.13.2.236"},{"key":"e_1_3_7_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2009.02972.x"},{"key":"e_1_3_7_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0507.2001.00656.x"},{"key":"e_1_3_7_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2018.07.011"},{"key":"e_1_3_7_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/head.12246"},{"key":"e_1_3_7_15_2","first-page":"229","article-title":"Invasive cutaneous mucormycosis caused by Absidia corymbifera after allogeneic bone marrow transplantation","volume":"18","author":"Jantunen E","year":"1996","unstructured":"Jantunen E, Kolho E, Ruutu P, et\u00a0al. Invasive cutaneous mucormycosis caused by Absidia corymbifera after allogeneic bone marrow transplantation. Bone Marrow Transplant 1996; 18: 229\u2013230.","journal-title":"Bone Marrow Transplant"},{"key":"e_1_3_7_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0163-4453(88)96570-X"},{"key":"e_1_3_7_17_2","doi-asserted-by":"publisher","DOI":"10.21037\/jtd.2019.12.53"},{"key":"e_1_3_7_18_2","first-page":"47","article-title":"[Favorable outcome of orbital nasal sinus mucormycosis complicating the induction of acute lymphoblastic leukemia]","volume":"2","author":"Gebhard F","year":"1995","unstructured":"Gebhard F, Chastagner P, Maillot D, et\u00a0al. [Favorable outcome of orbital nasal sinus mucormycosis complicating the induction of acute lymphoblastic leukemia]. 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