{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T13:21:31Z","timestamp":1777728091270,"version":"3.51.4"},"reference-count":27,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      We aimed to compare\n                      <jats:italic toggle=\"yes\">Demodex<\/jats:italic>\n                      positivity before and during the coronavirus disease 2019 pandemic.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Patients who underwent a standardized skin surface biopsy and direct microscopic examination for\n                      <jats:italic toggle=\"yes\">Demodex<\/jats:italic>\n                      species in the prepandemic or pandemic period at a tertiary care center were included. The positivity rates in the two periods were compared across age, sex, and months using a proportional Z-test. A\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009value &lt;0.05 was considered statistically significant.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In total, 573 and 523 patients were included in the pandemic and prepandemic periods, respectively.\n                      <jats:italic toggle=\"yes\">Demodex<\/jats:italic>\n                      positivity was significantly higher in the pandemic period (68.9%) than in the prepandemic period (50.5%)\n                      <jats:italic toggle=\"yes\">(p<\/jats:italic>\n                      \u2009&lt;\u20090.00001).\n                      <jats:italic toggle=\"yes\">Demodex<\/jats:italic>\n                      positivity increased significantly among male (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.00386) and female groups\n                      <jats:italic toggle=\"yes\">(p<\/jats:italic>\n                      \u2009&lt;\u20090.00001) in the pandemic period compared with that in the prepandemic period. Positivity rates increased in all age groups, with significant increases observed in those aged 10\u201325 (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.00006), 36\u201345 (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.0012), and 46\u201355\u2009(\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.01242) years.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      <jats:italic toggle=\"yes\">Demodex<\/jats:italic>\n                      positivity was higher in the pandemic period than in the prepandemic period, with significant increases observed during colder months. Furthermore, the increase in positivity was most prominent in patients aged 10\u201325 years, who spend more time in schools or crowded work places. Therefore, a possible association of face mask use and higher\n                      <jats:italic toggle=\"yes\">Demodex<\/jats:italic>\n                      positivity must be explored through future controlled studies.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/03000605251389395","type":"journal-article","created":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T00:20:40Z","timestamp":1764289240000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Changes in\n                    <i>Demodex<\/i>\n                    positivity before and during the coronavirus disease 2019 pandemic and the potential influence of pandemic-related factors"],"prefix":"10.1177","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0833-1854","authenticated-orcid":false,"given":"Ay\u015fe","family":"\u00d6zka\u00e7maz","sequence":"first","affiliation":[{"name":"Department of Medical Microbiology, Van Y\u00fcz\u00fcnc\u00fc Y\u0131l University Faculty of Medicine, T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hatice Uce","family":"\u00d6zkol","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Van Y\u00fcz\u00fcnc\u00fc Y\u0131l University Faculty of Medicine, T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet","family":"Parlak","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, Van Y\u00fcz\u00fcnc\u00fc Y\u0131l University Faculty of Medicine, T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zeynep B\u00fc\u015fra","family":"\u015eahin","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, Van Y\u00fcz\u00fcnc\u00fc Y\u0131l University Faculty of Medicine, T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ferit","family":"Ayaz","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, Van Y\u00fcz\u00fcnc\u00fc Y\u0131l University Faculty of Medicine, T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasemin","family":"Bayram","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, Van Y\u00fcz\u00fcnc\u00fc Y\u0131l University Faculty of Medicine, T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,11,27]]},"reference":[{"key":"e_1_3_8_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/dth.13103"},{"key":"e_1_3_8_3_2","first-page":"237","article-title":"The possible relation of Demodex and facial erythema in connective tissue diseases","volume":"18","author":"Erden A","year":"2023","unstructured":"Erden A, Arma\u011fan B, G\u00fcven SC, et\u00a0al. The possible relation of Demodex and facial erythema in connective tissue diseases. Iran J Parasitol 2023; 18: 237\u2013243.","journal-title":"Iran J Parasitol"},{"key":"e_1_3_8_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.parepi.2023.e00299"},{"key":"e_1_3_8_5_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10112533"},{"key":"e_1_3_8_6_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.849465"},{"key":"e_1_3_8_7_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.574910"},{"key":"e_1_3_8_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-020-0330-5"},{"key":"e_1_3_8_9_2","first-page":"393","article-title":"Dermatoparasitoses in referral patients to the laboratory","volume":"17","author":"Navi Z","year":"2022","unstructured":"Navi Z, Najafi F, Paknezhad N, et\u00a0al. Dermatoparasitoses in referral patients to the laboratory. 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