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The original left anterior descending artery was small and appeared occluded; it was initially misdiagnosed as a chronic total occlusion lesion. However, a displaced left anterior descending artery was identified during angiographic evaluation. Although a left main coronary artery arising from the right coronary sinus is uncommon (prevalence of 0.03%), to the best of our knowledge, this is the first reported case of an ectopic left anterior descending artery originating from the right coronary sinus.<\/jats:p>","DOI":"10.1177\/03000605261416659","type":"journal-article","created":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T10:33:32Z","timestamp":1769855612000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["A rare case of ectopic origin of the left anterior descending artery from the right coronary sinus misdiagnosed as a chronic total occlusion lesion"],"prefix":"10.1177","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5017-2837","authenticated-orcid":false,"given":"Wencai","family":"Jiang","sequence":"first","affiliation":[{"name":"Suining Central Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shiheng","family":"Zhou","sequence":"additional","affiliation":[{"name":"Suining Central Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanxuan","family":"Yang","sequence":"additional","affiliation":[{"name":"Suining Central Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yonghong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Suining Central Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gang","family":"Huang","sequence":"additional","affiliation":[{"name":"Suining Central Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuejun","family":"Deng","sequence":"additional","affiliation":[{"name":"Suining Central Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,1,31]]},"reference":[{"key":"e_1_3_7_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.121.055347"},{"key":"e_1_3_7_3_2","first-page":"e15584","article-title":"A case of anomalous left anterior descending artery originating from the right sinus of valsalva","volume":"13","author":"Patel N","year":"2021","unstructured":"Patel N, Bhogal S, Ramu V, et\u00a0al. 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