{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:06:26Z","timestamp":1787018786082,"version":"build-2736575974"},"reference-count":50,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To comprehensively examine hypertension- and heart failure\u2013related mortality rates in the United States to develop a targeted approach to health policy development.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We analyzed death certificates from the Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research database, focusing on mortality caused by hypertensive heart failure in adults aged \u226525 years from 2006 to 2020. Age-adjusted mortality rates per 1,000,000 and annual percent changes were calculated and categorized by year, sex, race, urban status, age group, and census region.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 268,545 deaths occurred due to hypertensive heart failure between 2006 and 2020. The overall age-adjusted mortality rates increased from 60.5 in 2006 to 134.9 in 2020. Males had higher age-adjusted mortality rates than women (76.6 vs. 73.8). Older-aged people exhibited significantly higher age-adjusted mortality rates than young and middle-aged adults. Age-adjusted mortality rates were highest in non-Hispanic Blacks\/African Americans and lowest in non-Hispanic Asians\/Pacific Islanders (126.8\u201343.6). Furthermore, age-adjusted mortality rates were highest in individuals from nonmetropolitan areas and the Western region.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Following a period of decline, the age-adjusted mortality rates increased until 2020. The highest age-adjusted mortality rates were observed in non-Hispanic Blacks and nonmetropolitan areas. An urgent restructuring of healthcare policy is needed to reduce heart failure-associated mortality.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/03000605261417063","type":"journal-article","created":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T03:11:13Z","timestamp":1775790673000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Demographics and mortality trends of hypertensive heart failure in the United States, 2006\u20132020: Insights from the CDC WONDER database"],"prefix":"10.1177","volume":"54","author":[{"given":"Muhammad","family":"Faizan","sequence":"first","affiliation":[{"name":"Department of Medicine, Hamad Medical Corporation, Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pramod","family":"Singh","sequence":"additional","affiliation":[{"name":"Barhabise Primary Health Care Centre, Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Syed Mohammad","family":"Haleem","sequence":"additional","affiliation":[{"name":"Department of Medicine, National Institute of Cardiovascular Diseases, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asad","family":"Zaman","sequence":"additional","affiliation":[{"name":"Department of Medicine, CMH Multan Institute of Medical Sciences, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Abdullah","family":"Humayun","sequence":"additional","affiliation":[{"name":"Department of Artificial Intelligence &amp; Oncology Research, Mayo Clinic, Scottsdale, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad","family":"Mubariz","sequence":"additional","affiliation":[{"name":"Department of Medicine, Akhtar Saeed Medical and Dental College, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdul Rafae","family":"Faisal","sequence":"additional","affiliation":[{"name":"Department of Medicine, CMH Multan Institute of Medical Sciences, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Faisal Naveed","family":"Akhtar","sequence":"additional","affiliation":[{"name":"Department of Medicine, CMH Multan Institute of Medical Sciences, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fnu","family":"Laiba","sequence":"additional","affiliation":[{"name":"Department of Medicine, Akhtar Saeed Medical and Dental College, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-5316-2329","authenticated-orcid":false,"given":"Rick","family":"Maity","sequence":"additional","affiliation":[{"name":"Indian Institute of Technology Kharagpur"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arkadeep","family":"Dhali","sequence":"additional","affiliation":[{"name":"Sheffield Teaching Hospitals NHS Foundation Trust, UK"},{"name":"School of Medicine and Population Health, University of Sheffield, UK"},{"name":"Deanery of Clinical Sciences, University of Edinburgh, UK"},{"name":"Faculty of Medicine, Imperial College London"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,4,9]]},"reference":[{"key":"e_1_3_9_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41569-021-00559-8"},{"key":"e_1_3_9_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2024.15563"},{"key":"e_1_3_9_4_2","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2022.753861"},{"key":"e_1_3_9_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41581-019-0244-2"},{"key":"e_1_3_9_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2023.102034"},{"key":"e_1_3_9_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcrp.2024.200326"},{"key":"e_1_3_9_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2021.05.022"},{"key":"e_1_3_9_9_2","first-page":"851","article-title":"Trends in heart failure\u2013related mortality among older adults in the United States from 1999-2019","volume":"10","author":"Siddiqi TJ","year":"2022","unstructured":"Siddiqi TJ, Khan Minhas AM, Greene SJ, et\u00a0al. 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